What Does Peracetic Acid Do as a Disinfectant?

Peracetic acid (PAA) is a powerful chemical compound used to eliminate harmful microorganisms across various environments. It is increasingly recognized for its effectiveness as both a disinfectant and sanitizer, helping maintain hygienic conditions and prevent contamination.

Understanding Peracetic Acid

Peracetic acid, also known as peroxyacetic acid, is an organic compound with the chemical formula CH₃CO₃H. It is a colorless liquid with a distinct, pungent, vinegar-like odor. PAA functions as a strong oxidizing agent, which is key to its disinfectant capabilities. It is commonly sold as an equilibrium mixture with acetic acid (vinegar), hydrogen peroxide, and water, which ensures its stability and sustained efficacy. PAA demonstrates broad-spectrum activity, effectively targeting a wide range of bacteria, viruses, fungi, and spores.

How Peracetic Acid Eliminates Microbes

Peracetic acid works by initiating an oxidative process that attacks the fundamental structures of microorganisms. Its strong oxidizing potential disrupts the outer cell membranes, leading to a loss of cell wall integrity, leakage of cellular contents, and cell destruction. PAA also denatures proteins and interferes with essential enzyme systems within the microorganism. It specifically oxidizes sulfhydryl and sulfur bonds in proteins, enzymes, and other metabolic components crucial for microbial survival. This non-specific, rapid oxidative action helps prevent microorganisms from developing resistance.

Where Peracetic Acid is Used

Peracetic acid is widely applied across numerous sectors. In the food processing industry, PAA sanitizes surfaces, equipment, and treats poultry, meat, and fresh produce. For example, it reduces pathogens like Salmonella and Campylobacter in poultry chillers. Healthcare facilities utilize PAA for high-level disinfection and sterilization of medical instruments, including endoscopes, often through automated systems. Its ability to sterilize at low temperatures makes it suitable for heat-sensitive devices. PAA is also employed in water treatment for disinfecting wastewater effluents and controlling biofilm formation in cooling towers.

Safe Handling and Environmental Impact

Handling concentrated peracetic acid requires specific safety precautions due to its corrosive and irritating nature. Proper ventilation and personal protective equipment, such as gloves, eye protection, and respiratory protection, are necessary to prevent exposure to vapors and direct contact. Concentrated forms can cause severe irritation to the skin, eyes, and respiratory system. Despite its potency, peracetic acid has a favorable environmental profile. It rapidly breaks down into harmless byproducts: acetic acid (vinegar), water, and oxygen. This decomposition leaves minimal residue and avoids the formation of toxic byproducts often associated with other disinfectants.