The measurement of oxygen levels in the bloodstream, known as SpO2, is a common, non-invasive reading used in clinical settings and at home. SpO2 provides a fast assessment of how well the body is transporting oxygen. Understanding this measurement is important because it offers a direct window into a person’s respiratory and circulatory well-being, reflecting the efficiency of the lungs and cardiovascular system.
What Does SpO2 Measure?
SpO2 stands for Saturation of Peripheral Oxygen. It represents the percentage of hemoglobin in the arterial blood that is saturated with oxygen. Hemoglobin, a protein within red blood cells, binds to oxygen molecules in the lungs and carries them throughout the body. The SpO2 value is a ratio indicating how many hemoglobin binding sites are currently occupied by oxygen relative to the maximum number they could carry.
This measurement is obtained non-invasively using a device called a pulse oximeter, typically clipped onto a finger or earlobe. Because it is a peripheral estimate, SpO2 is formally distinguished from SaO2, or Arterial Oxygen Saturation. SaO2 is determined invasively by analyzing a blood sample drawn directly from an artery (Arterial Blood Gas test). A healthy SpO2 value confirms the respiratory system is effectively oxygenating the blood. When this percentage falls, it signals the body may not be getting the oxygen it needs.
How Pulse Oximetry Works
The technology behind the SpO2 reading is pulse oximetry, which uses light to distinguish between oxygenated and deoxygenated blood. A pulse oximeter contains two small light-emitting diodes (LEDs) that shine red and infrared light through the tissue, usually a fingertip. The scientific principle relies on the fact that oxygenated and deoxygenated hemoglobin absorb these two wavelengths differently.
Oxygenated hemoglobin absorbs more infrared light, while deoxygenated hemoglobin absorbs more red light. A photodetector on the opposite side of the tissue measures the amount of each wavelength that passes through. The oximeter’s internal processor calculates the ratio of the two absorption levels, converting it into the SpO2 percentage. Crucially, the device must also isolate the pulsatile flow of arterial blood to ensure it measures saturation only in the arteries, which is the source of the “pulse” in the name.
Interpreting Your SpO2 Results
For a healthy individual at sea level, a normal resting SpO2 reading falls between 95% and 100%. This range indicates the body’s oxygen delivery system is working efficiently. Readings slightly lower, such as 93% or 94%, suggest the oxygen level is insufficient and should prompt consultation with a healthcare provider.
A reading that drops to 92% or lower indicates hypoxemia, which is a low level of oxygen in the blood. When the SpO2 level falls below 90%, it is defined as a medical situation that requires immediate attention. Such low numbers signify that organs and tissues are likely not receiving enough oxygen, a state known as hypoxia.
Low SpO2 results can signal underlying conditions, including issues with lung function, such as pneumonia, chronic obstructive pulmonary disease (COPD), or asthma. Problems with breathing or circulation can also cause saturation to drop. If a reading of 92% or below is accompanied by symptoms like shortness of breath, confusion, or bluish discoloration of the skin, seek emergency medical care immediately.
Factors Affecting Measurement Accuracy
While pulse oximetry is generally reliable, several physiological and environmental factors can lead to inaccurate or misleading SpO2 readings. Anything that obstructs light transmission through the tissue can compromise the reading. For instance, dark-colored nail polish or artificial nails can absorb the light, causing the oximeter to falsely report lower saturation.
Poor peripheral circulation or cold extremities also interfere with measurement. Reduced blood flow makes the device struggle to detect the necessary pulsatile arterial signal, resulting in an erroneous or nonexistent reading. Excessive movement, such as shivering or shaking, disrupts the sensor’s ability to capture light absorption patterns, leading to unreliable results.
Specific blood abnormalities can also skew the reading. For example, in carbon monoxide poisoning, the device cannot differentiate between oxygen and carbon monoxide bound to hemoglobin. Because carbon monoxide-bound hemoglobin is bright red, the oximeter may provide a falsely high reading, masking a severe lack of oxygen.

