The spinal cord is a long, tubular structure of nervous tissue that acts as the central information highway, linking the brain to the rest of the body. It is an extension of the central nervous system, beginning where the brainstem ends, and serves as the main pathway for communication. This structure is responsible for transmitting millions of electrical signals that enable movement, sensation, and the regulation of bodily functions.
Location and Protective Casing
The spinal cord is housed within the vertebral column, a bony structure made up of 33 stacked bones called vertebrae. It begins at the base of the skull, where it is continuous with the medulla oblongata of the brainstem, and extends down to the upper lumbar region. In most adults, the cord terminates around the level of the first or second lumbar vertebra (L1 or L2) in a tapered, cone-shaped structure called the conus medullaris.
This placement means the spinal cord does not run the entire length of the bony spine, allowing for safe procedures like a spinal tap in the lower back. Protection comes from the three layers of membranes known as the meninges. The outermost layer is the dura mater, a tough, fibrous sheath.
Just beneath the dura mater is the arachnoid mater, separated from the innermost layer by the subarachnoid space. This space is filled with cerebrospinal fluid (CSF), providing a buoyant cushion that absorbs shock and protects the nervous tissue. The innermost layer, the pia mater, is a delicate membrane that adheres directly to the surface of the spinal cord.
Gross Anatomy: Physical Appearance and Size
When viewed in isolation, the spinal cord appears as a slightly flattened, cylindrical structure, with a whitish or pinkish color due to the concentration of neural tissue and blood vessels. It measures approximately 40 to 50 centimeters (about 16 to 18 inches) in length in adults. The diameter is roughly 1 to 1.5 centimeters, similar in thickness to a person’s little finger.
The cord is not uniform in width along its length, featuring two noticeable bulges known as enlargements. The cervical enlargement, located in the neck region, is thicker because it contains a greater density of neurons necessary to manage the nerve supply for the upper limbs.
The lumbosacral enlargement in the lower back is widened to accommodate the increased number of neurons that manage sensory input and motor output for the legs. Below the conus medullaris, the cord gives way to a bundle of spinal nerves called the cauda equina, or “horse’s tail.” This collection of nerves continues downward to exit the lower vertebral column.
Internal Architecture: Gray and White Matter
A cross-section of the spinal cord reveals its internal organization, characterized by a distinct, H-shaped or butterfly-shaped region known as the gray matter. This central region is composed of nerve cell bodies, dendrites, and unmyelinated axons, serving as the main site for synaptic transmission and processing.
The gray matter is separated into three pairs of columns, or “horns,” each with a specific function. The dorsal horns receive sensory information, such as touch and pain, which enters the cord from the body. The ventral horns contain the cell bodies of motor neurons, which send signals out to control skeletal muscles.
Surrounding this central gray matter is the white matter, which takes its lighter color from the myelin sheaths coating the axons. These myelinated axons are bundled into tracts that run up and down the cord. These tracts are divided into columns that carry information, either ascending toward the brain or descending away from the brain, to different parts of the body.
Essential Functions: Transmission and Reflexes
The spinal cord facilitates electrochemical communication between the brain and the peripheral nervous system. It acts as a two-way pathway, using ascending tracts within the white matter to carry sensory information (such as touch, pain, temperature, and proprioception) from the body to the brain for processing.
The cord also uses descending tracts to transmit motor commands from the brain down to the muscles and glands. These signals control voluntary movements. This transmission function also regulates involuntary autonomic functions, such as breathing, heart rate, and blood pressure.
The spinal cord is a processing center for reflex actions. These are rapid, involuntary responses managed through neural circuits called reflex arcs. This mechanism allows for an immediate reaction to a stimulus, such as quickly pulling a hand away from something hot, before the signal reaches the brain for conscious perception.

