The fastest way to kill heartburn is to chew a calcium carbonate antacid tablet, which starts neutralizing stomach acid within minutes. If you don’t have antacids on hand, half a teaspoon of baking soda dissolved in a glass of cold water works similarly. But several other tactics can speed up relief or keep the burn from lingering, depending on what you have available.
Antacids: The Fastest Over-the-Counter Option
Chewable antacids containing calcium carbonate or magnesium hydroxide neutralize acid on contact. They’re the quickest medication option because they work locally in your stomach rather than needing to be absorbed into your bloodstream first. In a clinical trial of over 1,600 adults with frequent heartburn, about a third of people taking an antacid had relief within 15 minutes.
The tradeoff is that antacids wear off relatively fast, typically within one to two hours. A combination product pairing an antacid with an H2 blocker (like famotidine) gives you both: the antacid handles the immediate burn while the famotidine kicks in later and keeps acid suppressed for seven hours or more. In that same trial, 70% of people taking the combination still had relief at the seven-hour mark, compared to about 59% on the antacid alone.
Baking Soda in a Pinch
If you’re at home without antacids, plain baking soda is a legitimate substitute. It’s sodium bicarbonate, the same active ingredient in some commercial antacid products. Dissolve half a teaspoon in a full glass of cold water and drink it after meals. The Mayo Clinic notes you can repeat this dose every two hours, but don’t exceed five teaspoons in a day.
A few cautions make this a short-term fix only. Baking soda is high in sodium, so it can worsen high blood pressure, kidney disease, or swelling in the legs. Don’t use it for more than two weeks. And avoid taking it within one to two hours of other medications, because it can interfere with absorption. If you’re reaching for baking soda regularly, that’s a sign the underlying problem needs attention.
Alginate Products: A Physical Barrier
Alginate-based products (sold under brand names like Gaviscon) take a different approach. Instead of just neutralizing acid, they form a gel-like raft that floats on top of your stomach contents, physically blocking acid from splashing up into your esophagus. They begin working right away and can be taken with or right after a meal. This makes them especially useful for heartburn that hits during or shortly after eating.
Loosen Your Clothes
This sounds almost too simple, but it’s backed by real numbers. A study published in Gastroenterology found that a tight waist belt caused an eightfold increase in acid reflux after a meal. The belt doubled the number of reflux episodes (from 2 to 4) and dramatically slowed the time it took the esophagus to clear acid: 23 seconds without the belt versus 81 seconds with it. If you’re wearing a snug waistband, high-waisted jeans, or a tight belt, loosening or removing it can provide noticeable relief within minutes.
Change Your Position
Gravity is your friend during heartburn. If you’re lying flat, sit or stand up. This alone helps acid drain back down into your stomach. If you need to stay in bed, lie on your left side. In that position, your esophagus sits above your stomach, so acid clears out more quickly. Lying on your right side does the opposite, positioning your stomach above the opening to the esophagus and making reflux worse.
Elevating your upper body also helps. If you get heartburn at night, propping the head of your bed up by six to eight inches (using a wedge pillow or blocks under the bed frame, not just extra pillows) keeps acid where it belongs.
Chew Gum After Eating
Chewing sugar-free gum for 20 to 30 minutes after a meal is a surprisingly effective tactic. Chewing stimulates saliva production, and saliva is mildly alkaline, so it helps wash acid back down and neutralize what’s left behind. Research from the University of Dundee found that chewing gum doubled saliva flow and cut the time it took to clear acid from the esophagus from about 7 minutes down to roughly 2 minutes. Pick a non-mint flavor if mint tends to trigger your reflux.
What to Avoid Right Now
While you’re dealing with active heartburn, a few things will make it worse. Don’t lie down within two to three hours of eating. Avoid bending over, which physically pushes stomach contents toward your esophagus. Skip carbonated drinks, alcohol, coffee, and acidic or fatty foods until the episode passes. Smoking relaxes the muscle that keeps acid out of your esophagus, so if you smoke, this is one more reason the burn sticks around longer.
When Heartburn Isn’t Heartburn
Heartburn and heart attacks can feel remarkably similar. Even doctors sometimes can’t tell them apart without testing. Typical heartburn produces a burning sensation in the chest, often after eating, and responds to antacids. It may come with a sour taste or a small amount of fluid rising into your throat.
A heart attack is more likely to feel like pressure, tightness, or squeezing in your chest that spreads to your neck, jaw, or arms. It often comes with shortness of breath, cold sweats, lightheadedness, or sudden fatigue. If you experience any of those symptoms, especially if they’re new or more intense than your usual heartburn, treat it as a cardiac emergency.
Certain symptoms alongside heartburn also signal something more serious in the digestive tract: difficulty swallowing, pain when swallowing, unexplained weight loss, vomiting blood, or black tarry stools. These are considered alarm symptoms that warrant prompt medical evaluation.

