When a medical imaging report mentions a measurement like 12 mm of displacement in the spine, it refers to anterolisthesis. This condition describes the forward movement of one vertebral bone over the one directly beneath it. To understand the severity of this slippage, medical professionals use a standardized grading system. This system translates the physical measurement into a grade, which guides clinical decisions regarding monitoring and treatment.
Defining Vertebral Slippage
The general condition of a vertebral bone slipping out of alignment is known as spondylolisthesis. When the slippage is in the forward direction, it is specifically called anterolisthesis. This forward movement can compress surrounding nerves or destabilize the spine, potentially leading to pain and other neurological symptoms. The opposite condition, where a vertebra slips backward relative to the one below it, is termed retrolisthesis.
Quantifying the degree of slippage is done using two primary methods derived from lateral X-ray images. One method is the absolute measurement, which is the direct distance the top vertebra has moved, reported in millimeters, such as the 12 mm measurement. The relative measurement, however, expresses the displacement as a percentage. This percentage is calculated based on how far the slipping vertebra has moved compared to the total front-to-back width of the vertebral body beneath it.
It is this percentage calculation, rather than the absolute millimeter measurement, that determines the clinical grade of the slippage. The width of the vertebral bodies can vary significantly between individuals. Therefore, a 12 mm slip in one person may represent a different level of severity than the same 12 mm slip in another person. The percentage is a normalized value that accounts for this anatomical variability.
The Standard Grading Scale
The universally accepted method for classifying the severity of anterolisthesis is the Meyerding Classification System. This system uses the calculated percentage of slippage to assign one of five distinct grades. The classification is based on drawing lines on a lateral view X-ray to determine the exact degree of translation.
Grade 1 is defined by a forward slip up to 25% of the vertebral body width. Grade 2 occurs between 26% and 50%. These first two grades are often referred to as low-grade slips and frequently respond well to non-surgical management.
As slippage progresses, higher grades represent more significant instability and potential nerve involvement. Grade 3 is assigned when the vertebral body has moved forward between 51% and 75%. Grade 4 is severe, indicating a translation between 76% and 100%. The most extreme classification is Grade 5, often called spondyloptosis, representing displacement greater than 100%.
Determining the Grade for 12 mm Displacement
A direct measurement of 12 mm does not immediately correspond to a single, fixed grade in the Meyerding system because the grade depends on the underlying bone’s size. To convert the 12 mm displacement into a percentage, the measurement must be divided by the antero-posterior width of the stable vertebra below it, and then multiplied by 100. This calculation determines which of the Meyerding grades the 12 mm slip falls into.
The antero-posterior width of a typical lumbar vertebral body can vary, generally ranging from around 30 millimeters to over 45 millimeters. If the width is 45 millimeters, a 12 mm slip results in 26.7% displacement (\(12 \text{ mm} \div 45 \text{ mm} \times 100\)). This percentage places the anterolisthesis at the beginning of the Grade 2 range.
If the underlying vertebral body is narrower, such as 30 millimeters wide, the same 12 mm slip yields 40% displacement (\(12 \text{ mm} \div 30 \text{ mm} \times 100\)), remaining within Grade 2. If the body is particularly narrow (e.g., 23 millimeters), the calculation results in 52.2% displacement (\(12 \text{ mm} \div 23 \text{ mm} \times 100\)), crossing the threshold into Grade 3.
For a 12 mm anterolisthesis, the grade will most commonly be classified as Grade 2. However, depending on the patient’s individual anatomy, it can potentially be classified as a low-end Grade 3 slip. Slips in this range are considered moderate to significant and require ongoing monitoring.

