Supplemental oxygen therapy, while often a life-extending and necessary treatment, frequently causes uncomfortable side effects, primarily nasal dryness and irritation. The soreness stems from the constant flow of oxygen, which strips the natural moisture from the delicate mucous membranes lining the nose. Understanding the mechanisms that lead to this irritation is the first step in finding effective relief. Before implementing any changes to your treatment or using new products, always consult with your healthcare provider to ensure safety and compatibility with your medical needs.
Understanding the Source of Irritation
The dryness experienced during supplemental oxygen use is primarily due to desiccation. Oxygen delivered from a tank or concentrator is typically not humidified and contains very little moisture, unlike the air a person normally breathes. This dry gas bypasses the body’s natural humidification system in the upper airways, leading to the rapid depletion of moisture from the nasal passages. This irritation is sometimes referred to as rhinitis sicca.
A second source of soreness comes from the mechanical friction and pressure exerted by the nasal cannula itself. The constant rubbing of the prongs inside the nostrils, and the pressure applied by the tubing on the exterior skin, can lead to chafing, pressure sores, and skin breakdown. This mechanical irritation, combined with the dryness caused by the oxygen flow, creates an environment where the tissues are vulnerable to cracking and sometimes even minor nosebleeds.
Topical Solutions for Immediate Relief
Providing immediate comfort for a sore nose focuses on safely restoring moisture to the irritated tissues. It is paramount to avoid using petroleum-based products, such as petroleum jelly or common lip balms, inside the nostrils when using supplemental oxygen. Petroleum products are fuel sources, and when combined with concentrated oxygen, they create a significant fire risk because oxygen is a powerful accelerant. Using these products also carries the risk of exogenous lipoid pneumonia if the oil is accidentally inhaled into the lungs over time.
The safest topical alternatives are water-based nasal gels or specialized moisturizers formulated for oxygen users. These products, such as saline gels or those containing ingredients like sesame seed oil, help lubricate the nasal passages without posing a fire or aspiration hazard. Saline nasal sprays are also highly effective, utilizing a simple solution of salt and water to soothe and rehydrate the nasal membranes. Proper application involves using a clean finger or cotton swab to apply a thin layer of the water-based gel just inside the nostril opening, avoiding deep penetration into the nasal cavity.
Addressing Dryness Through Humidification and Equipment
Long-term management of oxygen-related dryness involves adjusting the delivery system to introduce moisture. One of the most effective methods is attaching a bubble humidifier to the oxygen source, which forces the oxygen through a container of water. Humidification is generally recommended for flow rates exceeding 3 to 4 liters per minute (LPM), though some guidelines suggest it is beneficial for any flow rate if dryness is a concern. When using a humidifier, it is important to exclusively use distilled water to prevent mineral buildup within the unit that could be inhaled.
The equipment itself should be regularly assessed to minimize mechanical irritation and pressure points. Ensure the nasal cannula is correctly sized and fits loosely enough to avoid constant friction against the skin behind the ears and around the cheeks. Some patients find softer, more flexible cannula materials provide greater comfort against sensitive skin. The tubing should be cleaned frequently according to the manufacturer’s instructions to prevent the buildup of bacteria that could potentially contribute to irritation or infection.
Warning Signs and When to Seek Medical Advice
While minor soreness and dryness are common, certain symptoms indicate a more serious issue that requires professional medical attention. Consult a healthcare provider if you experience persistent or heavy nosebleeds that do not stop with gentle pressure. Increasing pain, the development of deep cracks or fissures, or visible skin breakdown that does not heal with home care are also reasons to seek evaluation.
Signs of a possible infection include yellow or green discharge from the nose, increasing redness and swelling, or a fever accompanying the nasal discomfort. The appearance of pressure ulcers or sores that worsen or do not respond to adjustments in equipment fit also warrants medical advice.

