The cardiac index (CI) is a hemodynamic measurement that provides specific insight into the heart’s pumping efficiency relative to an individual’s physical size. It represents a refined version of the more general cardiac output, which only measures the total volume of blood pumped per minute. The CI is widely used in medicine to monitor circulation and determine if the heart is delivering sufficient oxygenated blood to meet the body’s metabolic demands.
Understanding Cardiac Index Calculation
The cardiac index is derived by dividing the cardiac output (CO) by the body surface area (BSA) of the patient, expressed by the formula CI = CO / BSA. Cardiac output is a direct measure of the volume of blood the heart ejects each minute, typically ranging from 4 to 8 liters per minute in a resting adult. This output is calculated as the product of the heart rate and the stroke volume, which is the amount of blood pushed out with each beat.
BSA is a calculation based on a person’s height and weight, representing a two-dimensional measure of the body’s exterior. Without this adjustment, a large individual would naturally have a higher cardiac output than a small person, even if both hearts were functioning optimally. This standardization ensures that a measured cardiac output is assessed against the individual’s metabolic needs, which are proportional to their body size. The resulting unit of measure is liters per minute per square meter (L/min/m²), effectively scaling the heart’s output to the person’s physical structure.
Normal Values and Interpretive Ranges
In a healthy, resting adult, the normal range for the cardiac index is between 2.5 and 4.0 L/min/m². This range signifies that the heart is successfully circulating an adequate volume of blood to perfuse all of the body’s tissues. Values outside of this range suggest an alteration in the body’s hemodynamic state.
A cardiac index below 2.5 L/min/m² often indicates a low-output state, suggesting the heart is not pumping enough blood to meet oxygen requirements. For instance, a value below 2.0 L/min/m² can be an indicator of cardiogenic shock, where the heart is failing to pump effectively. Conversely, a cardiac index above the normal range, sometimes exceeding 4.0 L/min/m², indicates a hyperdynamic state. Elevated values are frequently seen in conditions where the body’s metabolic demand is high, such as in severe infection or sepsis, or in cases of anemia. Both significantly low and significantly high values are associated with an increased risk of poor outcomes in critically ill patients.
Clinical Importance in Patient Care
The cardiac index is a precise tool for evaluating cardiac performance and monitoring the effectiveness of circulation in delivering oxygen to tissues. It is a parameter in intensive care settings, particularly for patients experiencing various forms of circulatory shock. The CI helps clinicians classify the type of shock and tailor specific treatment strategies, as different shock types present with distinct CI profiles.
In cardiogenic shock, which results from heart failure, the CI is characteristically low, often dipping below 2.2 L/min/m². This low CI guides the use of medications called inotropes, designed to increase the heart’s pumping strength. In contrast, septic shock, a form of distributive shock, often presents with a high CI in its early phases due to widespread blood vessel dilation, necessitating interventions like vasopressors to tighten vessels. Monitoring the cardiac index over time allows medical teams to track the patient’s response to therapy, such as administering intravenous fluids or adjusting drugs. A desired outcome is a CI that moves back toward the normal range, indicating improved tissue perfusion and oxygen delivery. In patients with heart failure, tracking the CI is fundamental for assessing the severity of the condition and determining the need for advanced support or mechanical circulatory devices.
Techniques Used for Measurement
Obtaining the data required to calculate the cardiac index involves various monitoring techniques that range from highly invasive to non-invasive. The traditional, highly accurate method is the use of a pulmonary artery catheter, often referred to as a Swan-Ganz catheter. This invasive device is threaded through a vein into the right side of the heart and into the pulmonary artery, where it measures cardiac output using thermodilution.
Due to the risks associated with invasive catheterization, minimally invasive technologies have become prevalent in clinical practice. These techniques require less complex access, such as a central venous or arterial line. Examples include transpulmonary thermodilution and lithium dilution, which provide continuous or near-continuous measurements of cardiac output.
Non-invasive methods are the least risky and include techniques like Doppler ultrasound and transthoracic echocardiography. These imaging techniques use sound waves to measure the velocity and volume of blood flowing through the heart’s chambers, providing the necessary stroke volume and heart rate data to calculate the cardiac output. Another non-invasive approach, thoracic electrical bioimpedance, measures changes in electrical resistance across the chest to estimate blood flow.

