A Caudal Epidural Steroid Injection (CESI) is a specialized, minimally invasive procedure used to treat chronic pain originating from the lower spine. It is a type of Epidural Steroid Injection (ESI). The term “caudal” refers to the tail end of the body, indicating the specific access point for this injection. This targeted treatment delivers anti-inflammatory medication directly to the source of nerve irritation. The goal is to calm inflamed spinal nerves that cause discomfort in the lower back and legs.
Defining the Caudal Epidural Space
The epidural space is a cushion of fat, connective tissue, and blood vessels that encircles the dural sac, which contains the spinal cord and spinal nerves. This space extends the entire length of the spine, and the caudal approach targets its lowest portion. The caudal epidural space is accessed through a natural opening in the sacrum, the large triangular bone at the base of the spine. This opening is called the sacral hiatus, located just above the tailbone.
The sacrum is formed by five fused vertebrae. The sacral hiatus exists because the posterior bony plates of the lowest segments fail to fully fuse. This hiatus is covered by the sacrococcygeal ligament, which the needle must penetrate to enter the epidural space. Injecting medication here allows it to flow upward, bathing the nerve roots in the lower lumbar and sacral regions simultaneously.
Conditions Treated with the Injection
The caudal approach is frequently employed to address diffuse pain conditions affecting the lower back and both legs. It is often preferred over other injection techniques when inflammation is widespread or when a patient has a history of previous spinal surgery. The injection targets pain resulting from irritation of the spinal nerve roots, a condition known as radiculopathy.
Specific diagnoses commonly treated include lumbar spinal stenosis, where the narrowing of the spinal canal compresses the nerves, and pain caused by herniated or bulging discs. It is also an established treatment for post-laminectomy syndrome, often called failed back surgery syndrome, where pain persists after an operation. Reducing inflammation around the affected nerves helps interrupt the pain signals transmitted to the brain.
Performing the Caudal ESI Procedure
The procedure is performed in an outpatient setting under sterile conditions and takes about fifteen minutes to complete. The patient is positioned face-down, or prone, on an X-ray table to allow clear access to the base of the spine. After the skin is cleaned with an antiseptic solution, a local anesthetic is administered to numb the injection site and minimize discomfort.
A specialized hollow needle is then advanced toward the sacral hiatus, guided by fluoroscopy, a live X-ray technology. Fluoroscopy provides real-time visualization of the needle’s path, ensuring precise placement within the caudal epidural space. This imaging guidance is paramount for safety and to prevent contact with the dural sac or surrounding structures.
Once the needle is correctly positioned, a small amount of contrast dye is injected, a step known as an epidurogram. The dye’s spread is monitored to confirm that the medication will flow widely within the epidural space, reaching the target nerve roots. Finally, the therapeutic mixture, consisting of a corticosteroid and a local anesthetic, is slowly administered.
Expected Outcomes and Post-Injection Care
Patients often experience a temporary numbing sensation in the lower back or legs immediately following the procedure due to the local anesthetic component. This initial effect may wear off within a few hours, and it is not uncommon for the original pain to return or even temporarily increase before the steroid medication begins to work. Patients must arrange for a ride home and refrain from driving or engaging in strenuous activities for the first 24 hours.
The anti-inflammatory effects of the corticosteroid become noticeable within two to seven days after the injection. The duration of pain relief varies significantly among individuals, but many report sustained improvement lasting anywhere from a few weeks to several months. For individuals with diabetes, blood sugar levels must be monitored closely, as the steroid can cause a temporary elevation. The injection is considered one component of a broader rehabilitation plan, often used to make physical therapy more effective.

