What Is a Neuroma in the Hand and How Is It Treated?

A neuroma is a benign, disorganized growth of nerve tissue that forms after a nerve is injured. This condition is a reaction by the body as it attempts to repair damaged nerve fibers, not a tumor. Neuromas commonly occur in the hand and wrist following trauma, such as a laceration, crush injury, or surgical procedure. This tangled nerve mass can lead to chronic pain and sensitivity, significantly affecting hand function.

Understanding Hand Neuromas: Definition and Symptoms

A neuroma is an accumulation of regenerating nerve axons and scar tissue that develops when a severed nerve cannot successfully reach its original connection point. The proximal end of the injured nerve attempts to regrow, but without a clear path, the sprouting axons become entangled, forming a bulbous, non-functional mass. In the hand, these masses frequently form on the digital nerves of the fingers.

Two main types of neuromas occur in the hand: the terminal neuroma and the neuroma-in-continuity. A terminal neuroma, often called a stump or amputation neuroma, forms at the end of a completely severed nerve, such as after a fingertip amputation. The neuroma-in-continuity occurs when the nerve is damaged by traction or crush but remains physically intact, causing focal swelling along the nerve’s length.

The symptoms of a hand neuroma result from the mechanical irritation of these sensitive, disorganized nerve endings. Patients often experience localized tenderness, which feels like a small, firm lump beneath the skin. Applying direct pressure to this mass typically triggers a sharp, electric shock sensation, known as lancinating pain.

Other common symptoms include burning pain, tingling (paresthesia), and an unpleasant, abnormal sensation called dysesthesia. Dysesthesia can manifest as allodynia, where light touch or a mild stimulus causes significant discomfort. These painful episodes are frequently worsened by hand movements, gripping objects, or any activity that puts mechanical stress on the affected area.

Diagnostic Methods for Nerve Injuries

The diagnostic process begins with a detailed patient history and a thorough physical examination to pinpoint the location of the pain. The most specific maneuver used to identify a neuroma is the application of Tinel’s sign. This test involves lightly tapping directly over the suspected nerve area to reproduce the characteristic electric shock or tingling sensation.

Imaging studies are often used to confirm the presence of the mass and exclude other potential causes of pain, such as a cyst or scar tissue. High-resolution ultrasound is particularly useful as it can visualize the nerve in real-time, showing focal enlargement or swelling. Ultrasound can also help measure the neuroma’s size and determine its relationship to adjacent structures.

Magnetic resonance imaging (MRI) provides a broader view of the anatomy and can help confirm the diagnosis by showing the fusiform swelling of the nerve. In some cases, a diagnostic nerve block is performed by injecting a small amount of local anesthetic directly around the suspected neuroma. If the injection temporarily relieves the patient’s pain, it confirms the neuroma is the source of the symptoms, guiding treatment.

Comprehensive Treatment Pathways

Treatment for a painful hand neuroma is typically phased, starting with non-surgical, conservative measures before considering surgery. Non-operative management focuses on reducing the nerve’s sensitivity and managing the associated pain. This approach often involves physical therapy, including desensitization exercises using various textures to help retrain the nerve and skin.

Protective splinting or padding can be used to shield the neuroma from direct pressure and irritation during daily activities. Pharmacological interventions include medications designed to treat nerve pain, such as anti-seizure or antidepressant drugs, which modulate pain signals. Therapeutic injections of a corticosteroid and local anesthetic mixture can also be administered to decrease inflammation and temporarily soothe the irritated nerve endings.

If conservative treatments fail to provide adequate relief, surgical intervention becomes the next option, with the primary goal being neurectomy, or surgical removal of the neuroma. Simple excision, however, carries a risk of recurrence, as the cut nerve end may regrow another painful mass. Advanced techniques are often employed to prevent this recurrence.

One common technique involves transposing the nerve stump by relocating it into a protected area, such as deep into muscle tissue or bone (intraosseous implantation), away from surface pressure. This provides a soft, non-irritating environment that prevents the nerve from being constantly stimulated. Other advanced surgical methods include using a nerve cap or conduit to seal the cut end, physically preventing disorganized axonal sprouting.

Highly specialized procedures, like Targeted Muscle Reinnervation (TMR) or Regenerative Peripheral Nerve Interface (RPNI), involve implanting the excised nerve end into a small, healthy piece of muscle. The muscle tissue provides a biological target for the regenerating axons, which effectively quiets the nerve and reduces neuropathic pain. The choice of surgical procedure depends on the neuroma’s location, the severity of symptoms, and the patient’s anatomy.