A Stellate Ganglion Block (SGB) is a minimally invasive medical procedure involving an injection of local anesthetic into a specific cluster of nerves in the neck. This technique is used primarily to manage chronic pain conditions and disorders related to an overactive nervous system. The block temporarily interrupts nerve signals, aiming to provide relief by resetting the body’s involuntary responses. It is a targeted therapeutic approach utilized when other treatments have not been fully effective.
Anatomy and Function of the Stellate Ganglion
The stellate ganglion, also known as the cervicothoracic ganglion, is a collection of sympathetic nerves located near the base of the neck, situated in front of the seventh cervical vertebra (C7) and the first rib. This star-shaped structure is formed by the fusion of two separate nerve ganglia, the inferior cervical ganglion and the first thoracic ganglion. As a central hub of the sympathetic nervous system, the stellate ganglion controls nerve signals traveling to the head, neck, upper chest, and arms. These nerves regulate involuntary functions like blood flow, sweating, and pain sensation in the upper extremities. The ganglion provides nearly all the sympathetic innervation for the entire ipsilateral upper limb, head, and face.
Mechanism of Action
The physiological principle behind the SGB is the temporary interruption of sympathetic nerve activity at the ganglion. A local anesthetic, such as ropivacaine, is injected near the stellate ganglion, blocking the flow of nerve signals through this specific pathway. This chemical blockade prevents the transmission of signals that cause pain, excessive vasoconstriction, or a heightened state of physiological arousal. By temporarily blocking these signals, the SGB essentially forces a reset of the overactive sympathetic nervous system. This process allows the nervous system to regain a more balanced, resting state, reducing the constant “fight-or-flight” response that can drive chronic pain and other symptoms. The interruption of the sympathetic signals can also lead to vasodilation, or widening of blood vessels, which improves blood flow to the affected limb.
Primary Indications for Treatment
The stellate ganglion block is used for a variety of conditions where sympathetic overactivity is believed to contribute to the symptoms. One of the primary uses is for Complex Regional Pain Syndrome (CRPS), a chronic pain condition usually affecting an arm, hand, leg, or foot. For CRPS, the SGB targets the excessive sympathetic signaling that causes the burning pain, swelling, and changes in skin temperature and color in the affected upper limb. By blocking these signals, the procedure helps break the cycle of pain transmission.
The SGB is also utilized for post-traumatic stress disorder (PTSD), where the procedure addresses the persistent state of hyperarousal and chronic anxiety. The block may help to modulate brain regions involved in the stress response, leading to a reduction in symptoms like hypervigilance and insomnia. Other indications include certain vascular conditions, such as Raynaud’s disease, where the block improves blood flow by relaxing constricted blood vessels. Additionally, it is used for chronic pain conditions like refractory angina, phantom limb pain, and cluster headaches.
The Procedure Steps and Immediate Results
The stellate ganglion block is typically performed in an outpatient setting and usually takes less than 30 minutes. The physician uses real-time imaging guidance, such as ultrasound or fluoroscopy, to ensure the precise placement of the needle and avoid nearby structures like blood vessels. The needle is inserted into the neck, often targeting the C6 or C7 vertebral level, and a local anesthetic is slowly administered to bathe the nerve cluster. A successful block is confirmed by the immediate, temporary onset of a set of expected physical signs known as Horner’s Syndrome. These signs appear on the same side of the face as the injection and include a drooping eyelid (ptosis), a constricted pupil (miosis), and facial flushing or warmth. These visible, temporary changes confirm that the medication has successfully reached and temporarily blocked the sympathetic nerve chain.
Safety Considerations and Post-Procedure Recovery
The SGB is considered a low-risk procedure when performed by a qualified professional using imaging guidance. Common, temporary side effects are directly related to the spread of the local anesthetic to adjacent nerves. These can include temporary hoarseness or a sensation of a lump in the throat if the medication affects the recurrent laryngeal nerve. Difficulty swallowing is also possible, but these effects resolve within a few hours as the anesthetic wears off, coinciding with the resolution of Horner’s Syndrome. Patients are monitored in a recovery area for about an hour to ensure no immediate complications occur. Patients must arrange for someone else to drive them home due to the temporary effects on the eye and potential mild dizziness. While rare, more serious complications can include nerve injury, bleeding, or pneumothorax (a collapsed lung). Patients are instructed to rest for the remainder of the day and avoid strenuous activity.

