What Is a Stereotactic Breast Biopsy?

A biopsy is a medical procedure used to remove a small sample of tissue from the body so it can be examined under a microscope. This examination is the only definitive way to determine if an abnormality is benign or malignant. A stereotactic breast biopsy is a minimally invasive technique that uses specialized imaging to precisely guide the collection of tissue from a suspicious area within the breast. This method offers an alternative to surgical biopsy, requiring only a small skin incision and providing a faster recovery time.

Indications for Stereotactic Biopsy

A stereotactic breast biopsy is primarily chosen when an abnormality is visible only on a mammogram and cannot be felt during a physical examination or located easily with ultrasound. This technique is especially suited for sampling small clusters of calcifications, known as microcalcifications, or subtle masses deep within the breast tissue. These tiny calcium deposits can sometimes be an early sign of breast cancer, making accurate sampling important for diagnosis.

The stereotactic method relies on a sophisticated system that takes X-ray images from two different angles. A computer then uses these images to calculate the precise, three-dimensional coordinates of the target lesion. This pinpoint accuracy allows the radiologist to guide the biopsy device directly to the area of concern.

Preparing for the Procedure

Before the procedure, patients receive specific instructions to ensure safety and prevent complications, particularly concerning bleeding. It is advised to stop taking blood-thinning medications, such as aspirin, ibuprofen (NSAIDs), or certain herbal supplements, for several days leading up to the biopsy. You should confirm the exact timeframe with your healthcare provider.

On the day of the procedure, you may be permitted to eat and drink normally, but avoid applying deodorant, lotion, powder, or perfume to the chest and underarm area, as these substances can interfere with the X-ray images. Wearing comfortable, two-piece clothing is recommended. You must arrange for transportation home, as driving is not allowed after the procedure, and bringing a supportive sports bra can help minimize discomfort.

The Step-by-Step Process

The stereotactic biopsy is performed while the patient lies face down on a specially designed table with an opening. The affected breast is positioned through this opening, allowing it to be gently compressed and stabilized, similar to a standard mammogram. Maintaining stillness is important throughout the process to ensure the accuracy of the targeting.

Once the breast is positioned, the radiologist uses the stereotactic imaging system to confirm the coordinates of the target area. A local anesthetic is then injected into the breast to numb the skin and deeper tissue, which may cause a brief stinging or burning sensation. After the area is numb, a very small skin incision, typically only a few millimeters wide, is made to allow the insertion of the biopsy needle.

The specialized biopsy device, often a vacuum-assisted core needle, is advanced to the precise coordinates calculated by the computer. Additional X-ray images are taken during this step to confirm the needle’s tip is accurately placed within the abnormality. Multiple small tissue samples are collected through the needle.

After the necessary samples have been retrieved, a tiny, inert metal clip, called a tissue marker, is placed at the biopsy site. This marker is important for future imaging, as it permanently identifies the exact location from which the tissue was removed. The needle is then withdrawn, and pressure is applied to the site to stop any bleeding before a small dressing is placed over the incision.

Post-Procedure Care and Follow-Up

Following the biopsy, patients are advised to apply a cold compress or ice pack to the site for several hours to minimize swelling and bruising. Bruising and mild tenderness are common side effects that usually resolve within a few weeks. Pain can be managed with an over-the-counter pain reliever like acetaminophen, but NSAIDs should be avoided for at least 24 hours to reduce the risk of bleeding.

Patients should keep the biopsy site clean and dry for the first 24 hours and avoid strenuous activities, heavy lifting, or vigorous exercise for about one to two days. Signs of complication, such as excessive bleeding, significant swelling, or infection (increasing redness or warmth), should be reported to a healthcare provider immediately. The collected tissue samples are sent to a laboratory, and the pathology results are available within two to three business days, after which a follow-up appointment is scheduled to discuss the findings.