The Diagnostic and Statistical Manual of Mental Disorders (DSM), published by the American Psychiatric Association, serves as the standard reference for classifying and diagnosing mental health conditions in the United States. This manual provides clinicians with a common language and specific criteria for accurate diagnosis and treatment planning. The term “Axis 1 disorder” refers to a classification system used in the previous version, the DSM-IV, which operated on a structured, multi-axial approach to assessment. This historical framework guided practitioners in evaluating a patient’s overall health by considering various factors beyond the primary mental health condition.
The Context of the DSM-IV Multi-Axial System
The DSM-IV, which was in use until 2013, employed a multi-axial system to ensure a comprehensive assessment of a person’s psychological, biological, and social circumstances. This system utilized five separate “Axes” to organize diagnostic and contextual information about the patient. Axis I was specifically designated for “Clinical Disorders” and other conditions that might be the focus of treatment, serving as the primary diagnosis.
The separation of diagnoses across the axes was intended to provide a holistic picture of the patient’s functioning. Axis I disorders were typically viewed as the principal focus of clinical attention, often representing acute symptoms or conditions that were episodic in nature. This distinguished them from the disorders placed on Axis II, which were reserved for Personality Disorders and Intellectual Disability.
The conditions listed on Axis II were considered more enduring, beginning earlier in life, and representing ingrained patterns of behavior or developmental deficits. The remaining axes covered non-diagnostic but relevant information for the overall case formulation. Axis III recorded any General Medical Conditions that might be related to the mental health issue or affect its treatment.
Axis IV documented Psychosocial and Environmental Problems, such as housing issues or employment trouble, that could influence the diagnosis or prognosis. Finally, Axis V provided a Global Assessment of Functioning (GAF) score, a single numerical rating representing the individual’s overall level of psychological, social, and occupational functioning.
Types of Conditions Classified Under Axis I
Axis I covered a broad spectrum of mental health conditions, including every diagnosable mental disorder except for personality disorders and intellectual disability. These conditions were considered treatable through various interventions, including medication and psychotherapy, and were often the reason an individual sought initial help. The major categories of Axis I disorders encompassed conditions that affect mood, perception, substance use, and behavior.
Mood Disorders were a major grouping on Axis I, including Major Depressive Disorder and Bipolar Disorder, which involves significant shifts between manic and depressive episodes. Anxiety Disorders also fell under this axis, covering conditions like Generalized Anxiety Disorder, Panic Disorder, and Post-Traumatic Stress Disorder (PTSD).
Psychotic Disorders, such as Schizophrenia, were listed on Axis I, characterized by disturbances in thought, perception, and behavior, often involving hallucinations or delusions. Substance-Related Disorders, including dependence and abuse of various substances, were also classified here.
Other diverse conditions were placed on Axis I, including Eating Disorders like Anorexia Nervosa and Bulimia Nervosa, which involve severe disturbances in eating habits and body image. Dissociative Disorders, such as Dissociative Identity Disorder, which involve disruptions in memory, consciousness, or identity, were also a part of this axis. Conditions usually first diagnosed in childhood, such as Attention-Deficit/Hyperactivity Disorder (ADHD), were also categorized under Axis I.
The Shift Away from the Axis System
The multi-axial system was abandoned with the publication of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) in 2013. The developers determined that the distinction between Axis I and Axis II lacked empirical support, creating an artificial separation between conditions that were often co-occurring. Many clinicians also found the system cumbersome in practice, leading to a streamlined, non-axial documentation approach.
The DSM-5 replaced the five axes with a single list of all mental disorders, integrating conditions formerly found on Axes I, II, and III. This change removed the formal hierarchy between clinical disorders and personality disorders, acknowledging that both types of conditions are equally significant and should be treated holistically. This new structure allows for a single, comprehensive diagnosis that includes all relevant mental and medical conditions.
Information previously contained in Axis IV (psychosocial and environmental problems) and Axis V (GAF score) is now captured through separate notations. Clinicians are encouraged to note these contextual factors, often using codes from the International Classification of Diseases (ICD), to maintain a focus on the patient’s environment and level of functioning. The GAF scale was removed due to concerns about its reliability, with the World Health Organization Disability Assessment Schedule (WHODAS) suggested as an alternative measure of functional impairment.
While the term “Axis 1 disorder” is no longer used in contemporary clinical settings, the specific conditions it described remain the primary focus of mental health treatment today. The disorders were simply re-categorized into the single, unified diagnostic framework of the DSM-5.

