Chaliponga, scientifically identified as Diplopterys cabrerana, is a perennial plant native to the Amazon river basin, spanning a wide geographical range across South America. Known by the Quechua name “chaliponga” or sometimes “chagropanga,” this species holds an important place in the traditional customs of indigenous cultures. Its leaves have long been cultivated and utilized as a botanical source for specific ceremonial preparations used for generations in the region.
Botanical Identity and Origin
Diplopterys cabrerana is classified within the Malpighiaceae family, a group of flowering plants. The plant takes the form of a climbing shrub or woody vine, thriving in the humid, tropical biome of the Amazon rainforest. Its habitat stretches across countries including Colombia, Ecuador, Peru, and Brazil, where it often flourishes near riverbanks.
The leaves are noticeably large, typically elliptical in shape, and possess a leathery texture. These leaves can measure up to 26 centimeters in length. While the name chacruna is sometimes used for D. cabrerana in parts of Ecuador, this common name is more often associated with the distinct plant Psychotria viridis, which belongs to the Rubiaceae family.
Primary Active Compounds
The psychoactive properties of Diplopterys cabrerana result from its potent tryptamine alkaloids. The most significant compound is N,N-Dimethyltryptamine (DMT), a naturally occurring substance found in the leaves and stems. Scientific analysis of leaf samples has revealed high concentrations of DMT, ranging from approximately 0.17% to 1.75% by dry weight.
DMT serves as the primary hallucinogenic agent, inducing profound alterations in sensory perception and consciousness by interacting with serotonin receptors in the brain, particularly the 5-HT2A receptor. The alkaloid profile also includes 5-MeO-DMT (5-Methoxy-N,N-dimethyltryptamine), a related structural analog. Trace amounts of other compounds, such as bufotenin and N-methyltetrahydro-beta-carboline, contribute to the overall chemical makeup.
Role in Traditional Amazonian Practices
Chaliponga’s primary role in Amazonian ethnobotany is as an admixture in the preparation of ceremonial decoctions, most famously Ayahuasca or Yagé. Indigenous groups combine the leaves of D. cabrerana with the bark of the Banisteriopsis caapi vine to create the psychoactive brew. The chaliponga leaves supply the vision-inducing DMT component necessary for the brew’s full effect.
These ceremonies are overseen by a ritual specialist, often referred to as a shaman or curandero. They are undertaken for purposes including spiritual healing, divination, and gaining insight into the root causes of illness or imbalance. The visionary experiences elicited by the brew are interpreted by the shaman as a tool for diagnosing physical, emotional, and spiritual ailments within the community.
The plant is regarded as a teacher or spirit guide, and the experiences are believed to facilitate communication with the spiritual world and provide profound personal and communal insights. The shaman guides the participants through the experience, often utilizing sacred songs known as ícaros to manage the intensity of the visions.
Safety Considerations and Legal Status
The consumption of Diplopterys cabrerana in ceremonial preparations carries significant safety considerations, particularly due to the pharmacological interaction between its DMT content and the beta-carboline alkaloids found in the B. caapi vine. These beta-carbolines act as Monoamine Oxidase Inhibitors (MAOIs), which are necessary to prevent the body’s natural enzymes from rapidly breaking down the orally ingested DMT.
MAOIs can interact adversely with a broad range of common medications, including Selective Serotonin Reuptake Inhibitors (SSRIs), certain tricyclic antidepressants, and some over-the-counter cold medicines containing dextromethorphan. This combination can precipitate Serotonin Syndrome, a potentially life-threatening condition characterized by symptoms such as agitation, high blood pressure, and elevated body temperature. Comprehensive medical screening is necessary for individuals considering participation, especially those with pre-existing heart conditions or serious mental health disorders like bipolar disorder.
Regarding legal status, the primary psychoactive compound in Chaliponga, DMT, is classified as a Schedule I controlled substance in the United States and is similarly regulated under the 1971 United Nations Convention on Psychotropic Substances. The legal status of the plant itself and the traditional decoction, Ayahuasca, is more complex and highly variable by jurisdiction. Many countries prohibit the brew due to its DMT content, though certain nations, such as Brazil and Peru, permit its use for religious or traditional purposes.

