The human abdomen is divided into four quadrants to help medical professionals accurately describe the location of organs, pain, or injuries. These quadrants are established by imaginary lines crossing at the belly button: the right upper, left upper, right lower, and left lower quadrants (RUQ, LUQ, RLQ, and LLQ). The left lower quadrant (LLQ) is the area to the left of the midline and below the umbilicus, extending into the left flank. This region contains structures important for digestion, waste elimination, and reproduction.
Segments of the Large Intestine
The primary digestive structures located within the left lower quadrant are the final portions of the large intestine: the descending colon and the sigmoid colon. The large intestine absorbs water and salts from unabsorbed food matter, consolidating it into solid waste. This consolidation process is largely completed as the material moves through the LLQ.
The descending colon extends downward on the left side of the abdomen, beginning after the splenic flexure (the bend beneath the spleen). This segment acts as a storage site for stool before it moves further down. The muscular walls facilitate peristalsis, the wave-like contractions that push formed stool toward the next section.
The descending colon connects to the sigmoid colon, an S-shaped segment residing mostly within the LLQ and the pelvic area. This section is highly mobile due to its attachment via the sigmoid mesocolon. The sigmoid colon’s main function is to store feces until the body is ready for elimination. Its flexible nature allows it to accommodate varying amounts of waste before passing it to the rectum.
Deep Structures and Mobile Contents
Beyond the large intestine, the left lower quadrant contains several other structures that traverse the area or are situated deep within the pelvis. The left ureter, a muscular tube that drains urine from the left kidney, passes down through the LLQ on its way to the bladder. Conditions affecting the ureter, such as kidney stones, can cause pain localized to this quadrant.
In individuals with female anatomy, the left ovary and fallopian tube are also located deep within the LLQ, resting within the pelvis. The fallopian tube connects the ovary to the uterus, serving as the site where fertilization often occurs. For those with male anatomy, the left spermatic cord, which contains structures like the vas deferens and blood vessels, passes through the inguinal canal in this region.
The small intestine, particularly the loops of the ileum and jejunum, is another structure commonly found in the LLQ. Although the small intestine is largely centralized in the umbilical region, its high degree of mobility means that loops frequently shift and occupy space in all four quadrants. The presence of these mobile loops means that pain in the LLQ may sometimes originate from the small intestine rather than the colon.
Musculature and Primary Blood Flow
The deep boundaries of the left lower quadrant are formed by the abdominal wall musculature, which provides structural support and protection. Muscles like the external and internal obliques, as well as the deeper transversus abdominis, form the anterior and lateral walls. Posteriorly, the psoas muscle runs vertically along the spine and contributes to the deep support of the region.
The LLQ receives its primary arterial blood supply from branches of the inferior mesenteric artery (IMA), which arises from the abdominal aorta. The IMA specifically supplies the descending and sigmoid colon, which are derived from the hindgut. Blood supply to the deeper pelvic structures, including the reproductive organs and the lower portion of the ureter, comes from the internal iliac artery. The external iliac vessels also pass through the LLQ to become the femoral vessels, supplying the lower limb.

