What Is Made Out of Oil? From Plastics to Medicine

Crude oil is used to make far more than gasoline. Only about 43% of a barrel of oil becomes gasoline, according to U.S. Department of Energy refining data. The rest is transformed into diesel, jet fuel, and a wide range of non-fuel products that show up in nearly every corner of daily life, from the clothes you wear to the medicine you take. Roughly 11 to 12% of all crude oil goes directly into making plastics and other synthetic materials.

How a Barrel of Oil Gets Divided

A standard barrel of crude oil holds 42 gallons. After refining, it yields roughly 19 gallons of gasoline, 10 gallons of diesel, and 4 gallons of jet fuel. The remaining 9 or so gallons become liquefied petroleum gases, heavy fuel oil, and a category called “other products” that accounts for about 15% of the barrel. That 15% is where most non-fuel items originate. Refineries heat crude oil and separate it into different components based on weight. The lighter fractions become fuels. The heavier fractions and chemical byproducts become the raw materials for plastics, synthetic fibers, pharmaceuticals, and thousands of everyday goods.

Plastics and Packaging

Plastics are the most visible non-fuel product of crude oil. The process starts with ethylene, sometimes called the “king of petrochemicals” because more commercial chemicals are produced from it than from any other intermediate. About half of all ethylene produced worldwide goes into making polyethylene, the single most common plastic on the planet.

Polyethylene shows up as shopping bags, milk containers, plastic wrap, bottle caps, industrial films, wire insulation, and pipes. Despite looking and feeling different, a thin grocery bag and a rigid milk jug are chemically the same material, just manufactured in different ways. Beyond packaging, polyethylene is used in food processing machinery, construction materials, and veterinary tools.

Other petroleum-derived plastics include polyvinyl chloride (PVC) for plumbing and flooring, polystyrene for disposable cups and insulation foam, and polyethylene terephthalate (PET) for water bottles and food containers. Collectively, these materials are lightweight, durable, and resistant to corrosion, which is why they replaced glass, metal, and wood in so many applications over the past century.

Clothing and Synthetic Fabrics

If you’re wearing a stretchy T-shirt, workout leggings, or a wrinkle-free dress shirt, there’s a good chance your clothing is partly made from oil. The three dominant synthetic fibers are polyester, nylon, and acrylic, all manufactured from petroleum byproducts. Spandex, the stretchy material in activewear and underwear, is also petroleum-derived.

Polyester (specifically PET fiber) is the most widely used synthetic fabric for clothing worldwide. It resists wrinkles, stains, and pests, which makes it popular for everything from athletic wear to bedsheets. Nylon was originally developed as an alternative to silk and is now found in stockings, raincoats, backpacks, and carpet. Acrylic mimics the feel of wool and appears in sweaters, blankets, and craft yarn. Even high-performance materials like Kevlar, used in body armor, and carbon fiber, used in aerospace, start with petroleum-based polymers.

Cosmetics and Personal Care Products

Many ingredients in your bathroom cabinet trace back to a barrel of crude oil. Petroleum jelly (sold under the brand name Vaseline, among others) was first refined from residue found on oil well walls in the 19th century. Mineral oil, paraffin wax, and petrolatum remain common in lotions, lip balms, and ointments because they create a seal on the skin that locks in moisture.

The petroleum connection goes deeper than the obvious ingredients. Fragrances labeled “parfum” on ingredient lists often contain petroleum-derived compounds. Phthalates, used to make fragrances last longer and plastics more flexible, are petroleum derivatives found in nail polish, hair spray, and some shampoos. Surfactants that make shampoo lather and toothpaste foam are frequently synthesized from petrochemicals as well.

Detergents and Cleaning Products

The cleaning agents in your laundry detergent, dish soap, and household sprays are largely built from petroleum. Surfactants are the key ingredient that lets soap dissolve grease, and the most common types, including linear alkylbenzene sulfonates (found in laundry and dishwasher detergent) and alpha-olefin sulfonates (found in liquid hand soaps and body washes), are synthesized from crude oil fractions. Without these petroleum-derived surfactants, modern detergents would not exist in their current form.

Medicine and Medical Devices

Pharmaceuticals and modern healthcare depend heavily on petroleum. Many common medications, including pain relievers, antidepressants, cholesterol-lowering drugs, diabetes medications, and antihistamines, are synthesized from petrochemical precursors. The active compounds in these drugs are built from carbon chains that originate in crude oil refining.

Beyond pills, the physical infrastructure of healthcare runs on petroleum-based plastics. Syringes, IV tubing, surgical gloves, sterile packaging, implants, and drug delivery devices are all made from petrochemical polymers. Plastics are central to the antiseptic model of modern medicine because they can be manufactured in sterile conditions, molded into precise shapes, and disposed of after a single use. Researchers are developing biodegradable alternatives made from renewable materials, but petroleum-based plastics still dominate medical supply chains.

Agriculture and Food Production

Oil-derived products play a role long before food reaches your plate. Petroleum distillates are used as active ingredients in pesticides, often marketed as “horticultural oils.” These products control pests physically by coating insects and blocking their ability to breathe. Mineral oil, naphtha, heavy fuel oil, and waxes all fall under the umbrella of petroleum distillates used in agricultural applications.

Natural gas, a close relative of crude oil, is the primary feedstock for producing ammonia-based fertilizers that support large-scale farming worldwide. And once food is harvested, it’s typically stored, shipped, and sold in petroleum-based plastic packaging, from shrink wrap on a pallet of produce to the PET clamshell holding your strawberries.

The Chemical Building Blocks Behind It All

Nearly every product on this list starts with the same handful of molecules. Ethylene is the most important: it’s the raw material for polyethylene plastic, PET bottles, antifreeze (ethylene glycol), polyester fabric, and styrene foam. Propylene, another petrochemical building block, becomes polypropylene (used in yogurt containers, bottle caps, and automotive parts). Benzene becomes nylon, certain pharmaceuticals, and synthetic rubber. Butadiene becomes the rubber in tires.

These few molecules, all cracked from crude oil at high temperatures, branch into an enormous family tree of products. Paints, solvents, adhesives, crayons, candles, roofing materials, asphalt for roads, synthetic rubber for tires, and even chewing gum base all connect back to a barrel of crude oil. The U.S. Energy Information Administration estimates there are more than 6,000 products that use petroleum as a feedstock, which is why oil remains deeply embedded in modern life even as energy systems shift toward renewables.