Polypoid mucosal thickening in the maxillary sinus is a descriptive phrase frequently appearing on imaging reports, such as computed tomography (CT) scans. This finding is not a specific disease but a radiologic sign indicating chronic inflammation within the largest of the paranasal sinuses. It serves as a visual marker for an underlying process that causes the delicate sinus lining to swell and change shape. Understanding this thickening requires exploring the sinus’s anatomy and the nature of the inflammatory response.
Understanding the Maxillary Sinus and Mucosal Thickening
The maxillary sinuses are the largest pair of paranasal sinuses, situated beneath the eyes within the cheekbones. These air-filled cavities are lined with a thin, continuous layer of ciliated respiratory tissue called mucosa. The primary function of this mucosal lining is to produce mucus that traps inhaled particles, and cilia sweep the mucus toward a small drainage opening, or ostium, into the nasal cavity.
Mucosal thickening occurs when this lining becomes swollen, a reaction to irritation or infection. While a healthy sinus lining is typically less than one millimeter thick, thickening exceeding three to four millimeters is reported as abnormal on imaging. The term “polypoid” specifies the shape of this swelling, indicating that the thickened mucosa is not uniformly flat but has an irregular, lumpy, or bulging appearance.
This specific polypoid morphology suggests a chronic inflammatory state. The continuous irritation causes the mucosal tissue to become edematous, accumulating fluid and immune cells. This results in a rounded, grape-like protrusion into the sinus cavity, reflecting a persistent inflammatory cycle.
Primary Causes and Associated Symptoms
Polypoid mucosal thickening is a consequence of chronic rhinosinusitis, which is persistent inflammation lasting twelve weeks or longer. This long-term inflammation often stems from impaired drainage of the sinus, caused by various factors that block the natural ostium. One common underlying cause is allergic inflammation, where sensitivity to environmental allergens triggers a sustained immune response in the sinus lining.
Another significant contributor is odontogenic sinusitis, which occurs when a dental infection spreads from an upper molar or premolar root into the floor of the closely related maxillary sinus. Given the intimate anatomical relationship between the posterior maxillary teeth and the sinus floor, periapical abscesses or complications from dental procedures can easily introduce bacteria, leading to localized inflammation. This dental-related infection must be specifically identified, as treating the thickened mucosa alone will not resolve the underlying tooth problem.
While mild or focal thickening may be completely asymptomatic, more extensive involvement can cause facial pain or pressure, particularly over the cheeks. Other common symptoms include nasal congestion, postnasal drip, and a reduced or altered sense of smell. These discomforts arise because the swollen, polypoid mucosa obstructs the sinus drainage pathway, trapping mucus and potentially leading to secondary bacterial infection.
Diagnostic Methods and Treatment Approaches
The initial finding of polypoid mucosal thickening is typically made through medical imaging, with a Computed Tomography (CT) scan being the preferred diagnostic tool. A CT scan provides high-resolution cross-sectional images, allowing physicians to accurately measure the extent and shape of the mucosal swelling. The CT scan provides a radiological finding, which must be correlated with a patient’s clinical history and symptoms for a definitive diagnosis.
Diagnosis begins with a thorough physical examination and a detailed review of symptoms to determine if the thickening is an incidental finding or the cause of a patient’s complaints. The treatment approach is focused on resolving the underlying cause of the chronic inflammation. Medical management is the first-line treatment for most cases.
This often involves the use of topical nasal steroids, which reduce mucosal inflammation and swelling over several weeks or months. If an active bacterial infection is suspected, a course of antibiotics may be prescribed to eliminate the infectious component. For cases where dental pathology is identified, the infection must be treated by a dentist or oral surgeon, which may involve a root canal or extraction.
When symptoms persist despite medical therapy, or if the polypoid thickening is severe enough to cause complete obstruction, surgical intervention may be considered. Functional Endoscopic Sinus Surgery (FESS) is a procedure performed through the nostrils to widen the natural sinus drainage pathways. The goal of FESS is to remove excess inflammatory tissue and create a larger opening, allowing topical medications to reach the sinus interior and promoting long-term ventilation and drainage.

