Pressure injuries, commonly known as bed sores or pressure ulcers, are localized damage to the skin and underlying soft tissue. This damage occurs when prolonged pressure, often over a bony prominence, compresses small blood vessels. This sustained compression restricts blood flow, causing a lack of oxygen and nutrients that leads to tissue breakdown. Topical treatments, such as specialized creams, are a supportive component of management. Overall care involves relieving the source of pressure, ensuring adequate nutrition, and using appropriate dressings alongside any cream.
Understanding Pressure Injury Stages
The effectiveness of any cream relates directly to the severity, or stage, of the pressure injury. The staging system classifies the depth of tissue damage to guide the correct treatment approach. A Stage 1 pressure injury presents as intact skin with a localized area of non-blanchable redness, indicating underlying tissue damage.
A Stage 2 pressure injury involves partial-thickness skin loss, extending through the epidermis and into the dermis. This stage may appear as a shallow open ulcer with a pink or red wound bed, or as an intact or ruptured serum-filled blister. Topical creams are significant in managing these first two stages, focusing on protection and promoting a moist healing environment.
Stage 3 or Stage 4 injuries represent a full-thickness loss of skin and tissue. Stage 3 wounds involve visible adipose tissue, while Stage 4 wounds expose fascia, muscle, tendon, ligament, or bone. These severe injuries require complex medical management, often involving surgical debridement and specialized dressings. They are generally beyond the scope of treatment with simple topical creams alone.
Categorizing Topical Treatments
The selection of a topical cream is determined by the specific goal of treatment, such as prevention, protection from moisture, or managing a bacterial load. The cream’s chemical properties must match the needs of the injury stage and the surrounding skin environment. These products are grouped into three main functional categories based on their active ingredients.
Barrier Creams
Barrier creams are primarily used for prevention and managing Stage 1 injuries, especially in areas exposed to bodily fluids. Ingredients like zinc oxide or dimethicone create a hydrophobic, physical layer on the skin’s surface. This protective barrier shields the skin from excessive moisture, such as urine or wound exudate, which can cause maceration. They are highly beneficial in preventing incontinence-associated dermatitis, a major risk factor for pressure injury development.
Zinc oxide forms a thick, opaque film on the skin, offering protection and mild astringent qualities. Dimethicone, a silicone-based compound, provides a breathable, water-repellent film that minimizes friction and shear forces. These creams should only be applied to intact or slightly damaged skin. Their occlusive nature can trap bacteria or interfere with healing in deeper, open wounds.
Antiseptic and Antibiotic Agents
Topical agents containing antiseptics or antibiotics are reserved for wounds exhibiting localized signs of infection or heavy bacterial colonization. Antiseptic creams, such as those containing cadexomer iodine, work by releasing iodine, which has broad-spectrum antimicrobial activity. This helps to reduce the bacterial burden and manage slough within the wound bed.
Antibiotic creams like silver sulfadiazine are used to prevent or treat localized infection in open wounds. These agents must be used judiciously and under medical supervision to avoid the risk of developing antibiotic resistance or causing toxicity to healthy tissue. Routine use of these agents over non-antimicrobial alternatives is often discouraged, highlighting the need for targeted application.
Moisturizers and Hydrogels
Moisturizers and hydrogels maintain a balanced moisture level, which is a prerequisite for optimal wound healing. Simple moisturizers keep the surrounding healthy skin pliable and resistant to friction and shear forces. For open wounds, hydrogels, composed largely of water-insoluble polymers, can be applied to rehydrate a dry wound bed.
The high water content of hydrogels aids in autolytic debridement, a natural process using the body’s own enzymes to break down nonviable tissue. By donating moisture, hydrogels soften the dead tissue, allowing it to be naturally lifted away. These moist-wound-healing principles are often applied to superficial, Stage 2 ulcers.
Proper Application and Dressing Protocols
The technique used to apply the topical agent is crucial for effective treatment. Before application, the wound must be cleansed using a gentle solution, such as sterile saline, to remove debris and loose tissue. For Stage 1 injuries, mild, pH-neutral soap and water may be used to clean the area without causing further irritation.
Topical creams, especially barrier products, should be applied in a thin, even layer sufficient to coat the skin. Over-application of thick creams creates a heavy buildup that is difficult to clean and may interfere with the skin’s ability to breathe. Care must also be taken to avoid scrubbing the affected area during cleansing, which increases friction and shear damage.
Following the application of the cream, an appropriate secondary dressing is necessary to maintain the wound environment and protect the area. Dressings like transparent films, hydrocolloids, or foam pads are chosen based on the wound’s characteristics, such as the amount of drainage. This secondary layer keeps the topical agent in place, manages wound exudate, and provides physical cushioning against further friction.
When to Seek Professional Medical Care
Topical creams and home care protocols are not a substitute for comprehensive medical evaluation and management, especially for advanced injuries. Immediate professional medical care is required if any injury is assessed as a Stage 3 or Stage 4, or if a deep tissue injury is suspected. These conditions involve significant tissue loss and require specialized debridement and systemic treatment.
Urgent consultation is needed if there are signs of a spreading or systemic infection. Symptoms include fever, a foul odor, or pus-like drainage. Spreading warmth, redness, or swelling around the injury suggests the infection is moving beyond the wound edges, potentially leading to cellulitis or sepsis. If a Stage 1 or Stage 2 injury shows no improvement after seven to ten days of consistent care, a healthcare provider should be consulted to reassess the treatment plan.

