What Is the Best Treatment for Arthritis in the Shoulder?

The best treatment for shoulder arthritis depends on how far the disease has progressed and whether your rotator cuff is intact. Most people start with a combination of anti-inflammatory medication, targeted exercises, and cortisone injections. When those stop providing relief, shoulder replacement surgery has a 92% implant survival rate at 10 years and consistently produces major improvements in pain and function.

Types of Shoulder Arthritis

Not all shoulder arthritis is the same, and the type you have shapes which treatments will work best. The shoulder has two joints: the ball-and-socket glenohumeral joint (where most arthritis occurs) and the smaller acromioclavicular (AC) joint at the top of the shoulder where the collarbone meets the shoulder blade.

Osteoarthritis is the most common form. The smooth cartilage covering the bones wears away over time, eventually leaving bone grinding against bone. This tends to develop gradually over years and is most common after age 50. Posttraumatic arthritis is essentially the same process, but it’s triggered by a prior injury like a fracture or dislocation rather than general wear.

Rheumatoid arthritis works differently. The immune system attacks the joint lining, damaging cartilage, ligaments, and bone. It typically affects both shoulder joints rather than just one. A fourth type, called rotator cuff tear arthropathy, develops when a large, long-standing rotator cuff tear allows the upper arm bone to shift upward and grind against the bony roof of the shoulder. Each of these types narrows the treatment options in different ways, particularly when it comes to surgery.

Anti-Inflammatory Medication

Over-the-counter NSAIDs like ibuprofen and naproxen are typically the first line of defense. They reduce both pain and the inflammation driving it. For people with mild to moderate symptoms, consistent use during flare-ups can make a meaningful difference in daily function. Current clinical guidelines from the American Academy of Orthopaedic Surgeons recommend against using opioids as routine or long-term pain management for shoulder osteoarthritis.

As for supplements like glucosamine, chondroitin, CBD oil, and other alternative treatments, the evidence isn’t strong enough for orthopedic experts to recommend them one way or the other. That doesn’t mean they can’t help individual people, but you shouldn’t rely on them as your primary treatment.

Exercises That Reduce Shoulder Pain

Physical therapy and home exercises are a core part of managing shoulder arthritis at every stage. The goal is twofold: maintain your range of motion so the joint doesn’t stiffen further, and strengthen the muscles around the shoulder to take stress off the damaged cartilage. The Hospital for Special Surgery recommends several specific exercises, all performed once daily:

  • Pendulum swings: Hold onto a chair for balance, bend slightly at the waist, and let your affected arm dangle. Shift your weight to swing the arm in circles, then front-to-back, then side-to-side. Repeat 30 times in each direction.
  • Overhead stretch with a cane or stick: Lie on your back holding a cane in both hands. Slowly lift it overhead until you feel a gentle stretch, then lower. Three sets of 10 repetitions.
  • Outward rotation stretch: Lie on your back with elbows bent at your sides, holding a cane. Rotate your hand outward using the cane for a gentle push. Three sets of 10.
  • Resistance band rows: Stand with good posture, holding a resistance band with arms at your sides. Draw your elbows backward, squeezing your shoulder blades together. Hold for 5 seconds. Three sets of 10.

These exercises should produce a gentle stretch, not sharp pain. If a movement consistently hurts, back off the intensity or ask a physical therapist for modifications. Consistency matters more than intensity here.

Cortisone and Hyaluronic Acid Injections

When oral medication and exercise aren’t enough, injections directly into the joint can provide targeted relief. Cortisone (a corticosteroid) is the most commonly used option. It reduces inflammation quickly, and many people feel significant improvement within days.

Hyaluronic acid injections, which aim to lubricate the joint, are sometimes used as well. Research comparing the two found that cortisone provides faster and more substantial pain relief than hyaluronic acid alone. A combination of both showed the best results in one clinical trial, reducing pain and disability scores by about 58% at one month, compared to roughly 44% for cortisone alone and just 14% for hyaluronic acid alone.

Injections also serve a diagnostic purpose. If a cortisone injection into the shoulder temporarily eliminates your pain, it confirms that arthritis in the joint is the source. If it provides no relief at all, your doctor will look for other explanations.

The limitation of injections is that they wear off, typically within weeks to a few months. They’re a tool for managing symptoms, not a long-term fix, and repeated cortisone injections can potentially weaken surrounding tissues over time.

When Surgery Becomes the Best Option

Surgery enters the conversation when conservative treatments no longer control your pain or your shoulder function has deteriorated to the point where daily activities are significantly affected. The main surgical option is shoulder replacement, and the type you receive depends largely on the condition of your rotator cuff.

An anatomic total shoulder replacement mirrors your natural anatomy: a metal ball replaces the humeral head and a plastic socket replaces the glenoid. This option works best when your rotator cuff tendons are intact. Research published in the Journal of Shoulder and Elbow Surgery found that patients with osteoarthritis and an intact rotator cuff who received an anatomic replacement outperformed those who received a reverse replacement in nearly every functional measure, including overhead reaching, lifting 10 pounds, returning to sports, and overall range of motion.

A reverse total shoulder replacement flips the anatomy, placing the ball on the socket side and the socket on the arm bone. This design was originally developed for patients whose rotator cuff is too damaged to support a standard replacement, but it’s now used more broadly. It relies on the deltoid muscle rather than the rotator cuff to power the shoulder. For people with rotator cuff tear arthropathy or severely damaged rotator cuffs, a reverse replacement is often the only viable surgical option.

How Long Shoulder Replacements Last

A systematic review and meta-analysis of national registry data found that total shoulder replacements have a pooled 10-year survival rate of 92%. Reverse total shoulder replacements performed specifically for osteoarthritis had an even higher survival rate of 94.4% at 10 years. Patient-reported outcomes showed substantial improvement from pre-surgery scores across the board.

Infection is the most significant complication, occurring in up to 4% of standard total shoulder replacements and about 2.4% of reverse replacements. Most complications are manageable, but they can require additional surgery.

Recovery After Shoulder Replacement

Recovery follows a gradual timeline. Within the first day or two after surgery, therapists typically begin gentle hand, wrist, and elbow exercises to prevent stiffness. During the first several weeks, you’ll work with a physical therapist on improving shoulder movement and early strengthening.

By two to three months, most people are progressing to joint stability exercises and light weight training. The shoulder continues to improve for months after that, and most people return to their usual activities within six months. Higher-demand activities like overhead sports or manual labor take longer, and some limitations may be permanent depending on the type of replacement and the condition of the shoulder before surgery.

If your rotator cuff is intact and you received an anatomic replacement, you can generally expect a higher ceiling for demanding physical activities than with a reverse replacement. That said, both types produce dramatic improvements in pain relief and quality of life compared to living with advanced shoulder arthritis.