The tooth eruption sequence describes the specific order and approximate timing in which teeth emerge through the gums and into the mouth. This biological process begins in infancy and continues into early adulthood. Following the correct sequence is important because it helps establish proper spacing and alignment for the entire dental arch. When the sequence is followed, it guides the development of the jaws and determines how the upper and lower teeth fit together, a relationship known as occlusion.
The Order of Primary Teeth
The eruption of primary (deciduous) teeth typically begins around six months of age, with all 20 teeth usually present by age three. The first teeth to appear are the mandibular central incisors (six to ten months), quickly followed by the maxillary central incisors (eight to twelve months).
The eruption then moves laterally to the incisors. The upper lateral incisors typically appear between nine and thirteen months, and the lower ones follow between ten and sixteen months. This pattern of lower teeth often preceding the upper teeth is common in the primary dentition.
The next teeth are the first molars, which generally erupt between 13 and 19 months, often appearing before the canines. The canines (cuspids) emerge between 16 and 23 months, filling the space between the lateral incisors and the first molars. The sequence concludes with the second molars, which usually emerge between 23 and 33 months, completing the primary arch.
The Order of Permanent Teeth
The transition to the permanent dentition (32 teeth) begins around age six. The first permanent teeth are the non-succedaneous first molars, which erupt behind the primary second molars, establishing the posterior bite. Simultaneously, the lower central incisors (succedaneous teeth) emerge between six and seven years.
Next, the upper central incisors and the lower lateral incisors emerge between seven and eight years. The upper lateral incisors appear between eight and nine years.
The eruption sequence for the remaining teeth often involves the premolars emerging before the canines. The first premolars appear between ten and eleven years, followed by the second premolars (ten to twelve years). The permanent canines erupt later (lower: nine to ten years; upper: eleven to twelve years). The second molars erupt between eleven and thirteen years, and the sequence ends with the third molars (wisdom teeth), typically between 17 and 21 years of age.
Biological and Environmental Influences on Timing
The precise timing of tooth eruption is influenced by inherent biological factors and external environmental conditions. Genetics play a substantial role, often showing similar patterns within families. Gender is another factor, as girls frequently experience tooth eruption earlier than boys.
Systemic health conditions also affect the pace of development. Endocrine disorders, such as hypothyroidism, can slow down general bodily development, resulting in delayed tooth emergence. Nutritional status is important, as deficiencies in micronutrients like Vitamin D and calcium can impede the proper formation and movement of teeth.
Environmental factors encountered early in life, including birth weight and overall growth rate, show associations with eruption timing. Low birth weight has been linked to a delay in the appearance of the first primary teeth. These influences do not typically change the order of the sequence but rather the age at which each tooth emerges.
When Eruption Sequence Deviates
A significant deviation from the expected sequence or timing can lead to dental health issues requiring professional attention. Delayed eruption occurs when a tooth is significantly late in emerging, often signaling that the tooth is blocked or that a systemic issue is affecting development.
An abnormal sequence can contribute to problems such as ectopic eruption, where a tooth emerges in the wrong position or angle. This can sometimes cause damage to the root of a neighboring tooth, such as when a permanent molar erupts under a primary molar, leading to premature loss and space loss.
The most common consequence of a sequence abnormality is malocclusion (an improper bite), often accompanied by severe crowding. When teeth emerge out of order, they may not reserve the necessary space for later-erupting teeth, causing permanent teeth to become displaced. A tooth may also become impacted, meaning it is completely blocked from emerging, often requiring orthodontic intervention. Monitoring the eruption sequence allows dental professionals to manage these issues early.

