The O-Shot (short for “Orgasm Shot”) is a nonsurgical procedure that uses platelet-rich plasma (PRP) drawn from your own blood and injects it into specific areas of the vagina to improve sexual function and, in some cases, reduce urinary leakage. It was developed by Charles Runels and has gained attention as a treatment for women experiencing low arousal, difficulty reaching orgasm, painful intercourse, or vaginal dryness.
How the Procedure Works
The O-Shot uses the same principle behind PRP therapies used in sports medicine and wound healing. A small amount of your blood is drawn and spun in a centrifuge to concentrate the platelets, which are cells packed with growth factors. These growth factors promote tissue repair, stimulate new blood vessel formation, and reduce inflammation. The concentrated plasma is then injected into two specific locations: the clitoris and the anterior vaginal wall near the G-spot, which is the erotic zone close to the urethra, as described by the American Society of Plastic Surgeons.
The idea is that flooding these areas with growth factors triggers a regeneration process. New blood vessels develop, nerve sensitivity increases, and the tissue becomes healthier and more responsive. Because the plasma comes from your own blood, there’s no risk of an allergic reaction or rejection.
What It’s Used For
The O-Shot targets a range of sexual health concerns. Women who seek the procedure typically experience one or more of the following: difficulty reaching orgasm, reduced sexual arousal, vaginal dryness, painful intercourse (dyspareunia), or low sexual desire. These symptoms fall under what clinicians call female sexual interest/arousal disorder or orgasmic disorder.
Beyond sexual function, the O-Shot has also been studied for mild to moderate stress urinary incontinence, the type of leakage that happens when you cough, sneeze, or exercise. A pilot study treating women with PRP injections to the anterior vaginal wall near the mid-urethra found that symptoms improved at both one month and six months after treatment, with no significant side effects reported. The researchers concluded that PRP is a reasonable option for mild to moderate cases, though the treatment appeared to trend toward slightly better results in younger women.
What to Expect During the Appointment
The entire procedure typically takes under 30 minutes. First, blood is drawn from your arm, similar to a routine blood test. While the blood is being processed in the centrifuge, a numbing cream is applied to the injection sites. Once the PRP is ready, it’s injected using a fine needle into the clitoris and the vaginal wall near the G-spot.
Most women experience no significant pain during the procedure, though some notice mild tenderness or sensitivity in the treated areas for 24 to 48 hours afterward. You can return to normal activities right away, with one exception: sexual activity is typically resumed after 24 to 48 hours.
Results Timeline
Some women notice improved sensitivity and arousal within days of the procedure. However, the full regeneration process takes longer. Most women reach optimal results around three months after treatment, as the growth factors continue stimulating tissue repair and new blood vessel formation during that window. Results generally last about a year, sometimes longer, after which some women choose to repeat the procedure.
Cost and Insurance
The O-Shot is considered an elective procedure and is not covered by insurance. Prices vary by provider and geographic location, but most clinics charge between $1,200 and $2,500 per treatment. Some providers offer package pricing for repeat sessions. Since there’s no standardized pricing, it’s worth comparing a few providers in your area, keeping in mind that the experience and training of the practitioner matters more than finding the lowest price.
Limitations Worth Knowing
The O-Shot is still a relatively new procedure, and the research base, while promising, consists mostly of small studies and pilot trials rather than large randomized controlled trials. The pilot study on urinary incontinence, for example, included only twenty women. Results also vary from person to person. Some women report dramatic improvement in arousal, lubrication, and orgasm intensity, while others notice more modest changes or need a second treatment to see meaningful results.
The procedure is not a fix for relationship issues, hormonal imbalances, or psychological factors that contribute to sexual dysfunction. It works at the tissue level, improving blood flow and sensitivity, so it’s most effective when the underlying issue is physical rather than emotional or hormonal. Women dealing with complex or longstanding sexual health concerns often get the best outcomes when PRP is part of a broader treatment approach rather than a standalone solution.