What Is Tricompartmental Osteoarthritis of the Knee?

Osteoarthritis (OA) is a common condition characterized by the gradual breakdown of protective cartilage within a joint. This degeneration leads to pain, stiffness, and reduced mobility as the cushioning between bones wears thin. Tricompartmental osteoarthritis of the knee represents the most severe and widespread form of this disease, involving damage to all three distinct sections of the joint. This makes the condition challenging to manage and often signifies an advanced stage of joint disease.

Understanding the Knee Compartments

The knee is a complex joint divided into three primary functional areas, known as compartments. The medial compartment is located on the inner side of the knee, where the femur meets the tibia. This area is the most common site for initial OA development because it bears the majority of the body’s weight during activities like walking.

The lateral compartment sits on the outer side of the knee, formed by the meeting surfaces of the outer femur and outer tibia. While less frequently affected than the medial side, its health is important for side-to-side stability and movement. The third section is the patellofemoral compartment, which is positioned at the front of the knee and involves the kneecap (patella) gliding along a groove in the front of the femur.

In less severe cases of knee OA, the disease may only affect one area (unicompartmental) or two areas (bicompartmental). Tricompartmental disease means that the cartilage surfaces in the medial, lateral, and patellofemoral areas are all experiencing significant deterioration. This widespread damage leads to a loss of the smooth, protective cartilage coating, resulting in bone-on-bone contact in multiple locations.

Symptoms and Impact of Tricompartmental Disease

The damage across all three compartments typically results in symptoms that are far more intense than those associated with single-compartment disease. Patients often experience persistent, deep-seated pain that is present not only during movement but also when resting or sleeping. This constant discomfort significantly affects the quality of life.

Severe joint stiffness is a hallmark of advanced tricompartmental OA, particularly noticeable in the morning or after prolonged periods of sitting. The loss of cartilage severely limits the range of motion, making simple actions like bending or climbing stairs a struggle. This reduced flexibility often leads to an impaired gait, with some individuals developing a noticeable limp or a bow-legged or knock-kneed appearance.

Another common manifestation is crepitus, a grating, grinding, or popping sensation and sound as the roughened joint surfaces move against each other. The joint may also exhibit instability, feeling as though it might buckle or give way without warning. Chronic inflammation leads to joint effusion, or “water on the knee,” which causes visible swelling and increased tenderness around the joint.

Diagnostic Confirmation and Assessment

A thorough physical examination assesses the joint for tenderness, swelling, and signs of muscle atrophy. The provider checks the patient’s range of motion and observes their gait, looking for any malalignment or instability. The presence of a grating feeling, or crepitus, during movement is a strong clinical indicator of surface irregularity.

Imaging studies are the definitive tools for confirming the diagnosis and assessing the severity across all three compartments. Standard X-rays are the primary method, as they clearly show characteristic signs of OA, such as joint space narrowing. The narrowing of the space between the bones in the medial, lateral, and patellofemoral areas confirms the tricompartmental involvement.

X-rays also reveal the presence of osteophytes, which are bony growths or spurs that develop at the joint margins. If there is a need to evaluate soft tissues such as ligaments or remaining cartilage more closely, a Magnetic Resonance Imaging (MRI) scan may be utilized.

Comprehensive Treatment Approaches

Treatment for tricompartmental OA involves a progression from non-surgical management to definitive surgical intervention. Initial conservative approaches aim to reduce pain and maintain function, beginning with lifestyle modifications such as weight management to decrease stress on the knee joints. Physical therapy focuses on strengthening the muscles surrounding the knee and preserving flexibility.

Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used to control pain and inflammation, while injections can provide temporary relief. Corticosteroid injections deliver anti-inflammatory medication directly into the joint. Viscosupplementation involves injecting a gel-like substance to supplement the joint’s natural lubricating fluid. For tricompartmental disease, these non-surgical methods may offer diminishing returns as the disease progresses to a severe, end-stage condition.

When conservative treatments no longer provide adequate pain relief or functional improvement, surgery becomes the primary option. Total Knee Replacement (TKR) is considered the standard treatment for advanced tricompartmental osteoarthritis. This procedure involves removing the damaged cartilage and bone surfaces from all three compartments and replacing them with artificial components made of metal and plastic. The goal of TKR is to eliminate the source of pain and restore the knee’s alignment and function.