What Ointment Is Good for Hand, Foot, and Mouth Disease?

Hand, Foot, and Mouth Disease (HFMD) is a common viral illness, typically caused by the Coxsackievirus, often affecting infants and young children. While the infection is usually mild and resolves within seven to ten days, the associated rash, blisters, and oral sores cause considerable pain and discomfort. Management focuses entirely on supportive care, aiming to alleviate symptoms until the body clears the virus. Topical solutions, including ointments and mouth rinses, play a significant role in soothing affected areas and improving the patient’s quality of life.

Over-the-Counter Topical Relief for Skin Blisters

The rash and blisters that appear on the hands, feet, and sometimes the buttocks, are best managed by protective topical agents. Applying barrier ointments helps shield the skin from irritation and promote a moist healing environment. Products containing zinc oxide, such as diaper rash creams, create a physical barrier on the skin’s surface. This protective layer helps dry out weeping blisters and reduces the chance of secondary irritation.

Petroleum jelly is another option for creating a simple, occlusive barrier that prevents moisture loss and keeps the lesions supple as they heal. Regular application of unscented, thick emollients or moisturizers can help reduce overall skin dryness and irritation, which is particularly useful if the rash causes itching. While calamine lotion is a traditional remedy, some experts suggest that simple emollients or topical products containing menthol are more effective for the specific itch associated with HFMD.

For localized pain or intense itching on the skin, a mild topical anesthetic may be considered. Over-the-counter creams or lotions containing pramoxine hydrochloride work as a local anesthetic to temporarily block nerve signals that transmit the sensation of itching or pain. These topical treatments should only be applied to intact skin and not to large areas, deep wounds, or open blisters, as this can increase absorption and potential side effects. It is also important to note that topical steroid creams, like hydrocortisone, should generally be avoided for viral rashes unless specifically instructed by a healthcare provider.

Targeted Treatments for Painful Oral Sores

The small, painful ulcers that form inside the mouth and throat often present the biggest challenge, as they interfere with eating and drinking, posing a risk of dehydration. Topical relief for oral sores must focus on numbing the area to allow for fluid intake. Simple, non-medicated rinses offer a gentle way to cleanse and soothe the mouth.

A warm saline solution, made by dissolving salt in water, can be swished around the mouth by older children or adults to provide temporary comfort. A mixture often referred to as “Magic Mouthwash” can be created using equal parts of a liquid antacid (like Maalox) and a liquid antihistamine (such as diphenhydramine). The antacid component helps coat the sores, while the antihistamine provides a localized numbing and anti-inflammatory effect.

For infants and very young children who cannot reliably swish and spit, this mixture can be carefully dabbed onto visible sores with a cotton swab. Caution is necessary with specific medicated oral anesthetics, especially in young children. Topical products containing benzocaine should not be used in children under two years old due to the rare but serious risk of methemoglobinemia, a condition that reduces the blood’s ability to carry oxygen. Discussing the use of any anesthetic mouth rinse with a healthcare provider is recommended before application.

Knowing When to Consult a Doctor

While Hand, Foot, and Mouth Disease is typically a self-limiting illness, medical consultation is necessary if symptoms become severe or complications arise. The most immediate concern is dehydration, particularly in infants and young children who refuse to drink due to painful swallowing. Signs of dehydration include a dry or sticky mouth, the absence of tears when crying, sunken eyes, or a significant decrease in urination, such as no wet diaper for four to six hours.

A doctor should also be consulted if there are signs of a secondary bacterial infection developing in the skin blisters. This may be indicated by increased redness, swelling, warmth, or the presence of pus or yellow discharge from the lesions. Furthermore, if a high fever (above 102°F) persists for more than three days, or if the patient exhibits unusual symptoms like severe headache, neck stiffness, unusual sleepiness, or extreme irritability, immediate medical attention is required.

In cases of severe pain that is not managed by over-the-counter options, a healthcare provider may prescribe stronger solutions. These prescription-strength topical anesthetics or specialized oral rinses often contain ingredients not available over the counter. Although HFMD is a viral infection, the physician can rule out rare, severe forms of the illness or other complications, ensuring the patient receives appropriate supportive care.