The organ situated directly under the rib cage on the right side of the body is the liver. This large, wedge-shaped organ occupies the majority of the space in the upper right section of the abdomen, known as the Right Upper Quadrant. The rib cage provides a substantial layer of protection, shielding this prominent organ from external damage.
The Dominant Organ: The Liver
The liver is the largest internal organ, often weighing around three pounds in an adult, and is positioned high up in the abdomen, nestled beneath the diaphragm. Its size requires the bony protection of the lower rib cage. The liver performs hundreds of functions necessary for life.
One of the liver’s primary tasks is detoxification, acting as the body’s filtration system for the blood. It processes and neutralizes harmful substances, including medications, alcohol, and metabolic byproducts, converting them into forms that can be safely excreted. The liver is also a central regulator of the body’s metabolism, storing glucose as glycogen. It releases this glucose into the bloodstream to maintain steady blood sugar levels and ensure a continuous energy supply.
The liver also produces bile, a greenish-yellow fluid essential for digestion. Bile contains acids and salts that emulsify fats, breaking large fat globules into smaller ones. This production of bile supports the breakdown and utilization of dietary fats.
Other Key Organs in the Area
While the liver dominates the space, several other organs reside or partially extend into the Right Upper Quadrant. Directly tucked beneath the liver is the gallbladder, a small, pear-shaped organ connected by a network of ducts. Its role is to store and concentrate the bile produced by the liver, releasing it into the small intestine when food is consumed.
The upper portion of the right kidney is also situated in this quadrant, lying toward the back of the body. The kidneys filter blood to remove waste products and excess water, converting them into urine. This location near the ribs provides partial protection for the upper part of this organ.
The large intestine also makes a turn in this region at the hepatic flexure, where the ascending colon meets the transverse colon. This section of the colon is involved in the final stages of digestion, absorbing water and electrolytes before waste material moves toward excretion.
Understanding Upper Right Quadrant Discomfort
Discomfort under the right rib cage often signals an issue with one of the organs located in the Right Upper Quadrant. Pain originating from the gallbladder, frequently caused by gallstones blocking a bile duct, is a common source of intense ache. Liver inflammation or swelling, such as from hepatitis or a fatty liver condition, can also cause a dull, persistent ache due to the stretching of the organ’s outer capsule.
Symptoms that progress beyond minor discomfort require immediate medical attention. Sharp, sudden pain that rapidly increases in intensity may indicate a serious condition like acute gallbladder inflammation. Pain that radiates from the front to the back or to the right shoulder blade is a classic symptom associated with gallbladder issues.
Specific visual or systemic signs should prompt a medical evaluation. The presence of jaundice, a yellowing of the skin and eyes, suggests a problem with bile flow or liver function. Unexplained fever, persistent nausea, or vomiting alongside the pain are also warning signs.

