The L5-S1 segment is the junction between the fifth lumbar vertebra (L5) and the sacrum (S1). Often called the lumbosacral junction, it forms the base of the mobile spine. It is the lowest level of the spinal column that contains a disc and functions as a motion segment. This region bears the entire weight of the upper body.
The Anatomical Location of L5-S1
The L5-S1 segment includes the L5 vertebra, the sacrum, and the intervertebral disc between them. The L5 vertebra rests directly on the sacrum, a triangular bone formed by five fused vertebrae (S1-S5). The intervertebral disc acts as a thick cushion and shock absorber for the spine.
This disc facilitates biomechanical movement, including the flexion and extension required for normal posture and activity. The L5-S1 segment is subjected to the greatest concentration of shear and compressive forces in the lower back. It serves as the primary transition point for transferring the weight of the torso and head onto the pelvis and lower limbs. This mechanical stress makes the area susceptible to wear and tear.
Motor and Sensory Regions Controlled by L5 and S1 Nerves
The L5 and S1 spinal nerves exit the spinal canal at this level, extending into the lower body to provide motor function and sensation. These nerve roots innervate specific muscle groups (myotomes) and distinct areas of skin (dermatomes). The distribution of these nerves determines which parts of the body are affected by L5-S1 issues.
L5 Nerve Root
The L5 nerve root primarily controls muscles involved in ankle dorsiflexion (lifting the foot toward the shin). It also innervates the muscles that allow for the extension of the great toe. Loss of function in these muscles can impact the ability to clear the foot during walking.
The L5 dermatome covers the lateral side of the lower leg, wraps around the front of the ankle, and extends across the top of the foot. Sensation is often tested over the third metatarsal head. Sensory change or pain following this path suggests L5 nerve root involvement.
S1 Nerve Root
The S1 nerve root governs the motor function of muscles responsible for ankle plantar flexion (pointing the foot downward). It contributes to the strength of the calf muscles and provides some innervation to the hamstring muscles. This nerve root is a major contributor to the push-off phase during walking and running.
The S1 dermatome is located along the back of the leg and calf. This sensory area continues down to the outer side of the ankle, covering the sole and heel of the foot. A specific point for testing S1 sensation is the lateral aspect of the calcaneus (the side of the heel). Compression or irritation at L5-S1 produces symptoms that follow these pathways into the leg and foot.
Common Manifestations of L5-S1 Dysfunction
When anatomical structures of the L5-S1 segment, such as a herniated disc, compress the exiting nerve roots, the resulting symptoms follow the specific distributions described. This nerve root irritation is medically termed radiculopathy. The most common manifestation is sciatica, characterized by sharp, shooting, or burning pain that radiates from the lower back or buttock down the back of the leg.
L5 Symptoms
Compromise of the L5 nerve root frequently leads to muscle weakness that interferes with normal walking patterns. A distinct symptom is foot drop, where the person has difficulty lifting the front part of the foot, causing the toes to drag while walking. Sensory changes manifest as numbness, tingling, or a “pins and needles” sensation across the top of the foot and the big toe.
S1 Symptoms
Irritation of the S1 nerve root results in radiating pain along its pathway, often extending to the heel and outer foot. The motor deficit involves weakness in plantar flexion, making it challenging to stand on the toes or maintain ankle stability. Sensory loss for S1 is felt in the calf, the outside of the foot, and the heel.
In rare and severe cases, central compression at the L5-S1 level can affect the cauda equina, a group of nerves including the lower sacral nerves (S2-S5). Compression of these nerves is an urgent medical matter. It can cause saddle anesthesia (numbness in the groin and inner thigh) and loss of bladder or bowel control. These signs indicate significant nerve compromise extending beyond the L5 and S1 distributions.

