What to Do for a Sinus Infection: Remedies That Work

Most sinus infections are caused by viruses and clear up on their own within seven to ten days. The best thing you can do is manage your symptoms at home while your body fights off the infection. Antibiotics won’t help in the majority of cases, and even bacterial sinus infections often resolve without them.

How to Tell What You’re Dealing With

Viruses cause most sinus infections. That means the playbook is similar to treating a cold: support your body, control your symptoms, and wait it out. The typical timeline is one to two weeks, though some people have lingering symptoms for up to four weeks.

A smaller number of sinus infections are bacterial. The key differences are in timing and pattern. You likely have a bacterial infection if your symptoms last more than ten days without improving, if they get noticeably worse after starting to get better, or if you have a fever lasting longer than three to four days. Even then, many doctors will recommend a period of watchful waiting (three to seven days) before prescribing antibiotics, because bacterial sinus infections frequently resolve on their own too.

Nasal Irrigation: The Single Most Helpful Step

Rinsing your nasal passages with saline is one of the most effective things you can do. It physically flushes out mucus, allergens, and irritants, reducing the congestion that makes sinus infections miserable. You can use a neti pot, squeeze bottle, or bulb syringe with a premixed saline packet or a homemade solution of distilled (not tap) water and non-iodized salt.

You can safely rinse once or twice a day while you have symptoms. Studies show that both children and adults who use nasal irrigation regularly see improved symptoms for up to three months. Some people continue rinsing a few times a week even after they recover to help prevent future infections.

Over-the-Counter Medications That Help

No medication will speed up your recovery from a sinus infection, but several can make you significantly more comfortable while you heal.

Decongestants

Oral decongestants containing pseudoephedrine (sold as Sudafed and found in combination products like Advil Cold and Sinus) work by shrinking swollen blood vessels in your nasal passages, which opens your airways. These are kept behind the pharmacy counter in the U.S., so you’ll need to ask for them. Phenylephrine, the ingredient in many decongestants sitting on the shelf, has been found to be far less effective.

Decongestant nasal sprays containing oxymetazoline (Afrin) work faster and more directly, but they come with a critical limitation: do not use them for more than three days. After about three days, the spray starts depriving your nasal tissue of blood flow, which triggers inflammation and causes your congestion to come back worse than before. This rebound effect, called rhinitis medicamentosa, can create a cycle where you feel like you need the spray constantly. Stick to the three-day limit.

Pain Relievers

Acetaminophen (Tylenol) or ibuprofen (Advil, Motrin) can reduce the facial pain, pressure, and headache that come with sinus infections. Ibuprofen has the added benefit of reducing inflammation. Either one also helps if you have a fever.

Other Helpful Options

Guaifenesin (Mucinex) is an expectorant that thins mucus, making it easier to drain. It won’t unclog your sinuses on its own, but paired with hydration and nasal irrigation, it can help keep things moving. Antihistamines are generally not recommended for sinus infections unless allergies are a contributing factor, because they can thicken mucus and slow drainage.

Simple Home Strategies That Make a Difference

Beyond medication, a few low-effort habits can meaningfully reduce how bad you feel:

  • Steam. Breathing in warm, moist air from a hot shower, a bowl of steaming water, or a warm compress over your face helps loosen mucus and soothe irritated tissue. Even five to ten minutes can provide temporary relief.
  • Hydration. Drinking plenty of fluids keeps mucus thin and easier to drain. Water, broth, and herbal tea all count.
  • Elevation. Sleeping with your head slightly raised (an extra pillow works) helps your sinuses drain overnight and reduces the pressure buildup that makes mornings especially miserable.
  • Humidity. Dry air irritates inflamed sinuses. A cool-mist humidifier in your bedroom can help, especially in winter.

What About Supplements?

Bromelain, an enzyme found in pineapple, has gotten attention as a natural option for sinus symptoms. A 2024 review of 54 studies concluded that bromelain helped relieve sinusitis symptoms, likely because of its anti-inflammatory properties. However, the National Center for Complementary and Integrative Health notes there isn’t enough high-quality research yet to confirm these benefits. If you want to try it, typical doses range from 80 to 320 milligrams taken two to three times daily, but there’s no established standard. It’s available as capsules and tablets.

When Antibiotics Actually Make Sense

Antibiotics are only useful for bacterial sinus infections, and even then, guidelines recommend trying symptomatic treatment first for most people. The criteria that point toward needing antibiotics are straightforward: symptoms lasting more than ten days with no improvement, symptoms that clearly worsen after initially getting better, or a high fever with severe facial pain and thick nasal discharge lasting three to four days or more.

If your doctor does prescribe antibiotics, you should start feeling better within a few days of starting them. Symptomatic treatment remains the foundation of care regardless. Saline rinses, decongestants, and pain relievers work the same whether the cause is viral or bacterial.

Symptoms That Need Urgent Attention

Serious complications from sinus infections are uncommon, but they can happen. The infection can, in rare cases, spread to surrounding structures including the bones, the skin, or the membranes around the brain and spinal cord. Get medical attention right away if you notice swelling or redness around your eyes, swelling of your forehead, a severe headache that feels different from typical sinus pressure, or a high fever. These can signal a spreading infection that needs immediate treatment.