What to Do for ED: Causes, Treatments & Options

Erectile dysfunction is common, treatable, and often a sign that something else in your body deserves attention. About 52% of men between ages 40 and 70 experience some degree of ED, and the likelihood increases with age, rising from roughly 39% at age 40 to 67% by age 70. The good news: most men have several effective options, from lifestyle changes to medications to therapy, and the right approach depends on what’s causing the problem.

Why Erections Stop Working

An erection is essentially a blood flow event. During arousal, nerves in the penis release a chemical signal that triggers the production of a molecule called cGMP. This molecule relaxes the smooth muscle in penile blood vessels, allowing them to widen and fill with blood. An enzyme called PDE5 naturally breaks down cGMP over time, which is how an erection eventually subsides. ED happens when something disrupts this process, whether it’s reduced blood flow, nerve damage, hormonal changes, or anxiety that prevents the arousal signal from firing properly.

This is why ED often has a physical root cause even when it feels like a mental one. Narrowed or stiff blood vessels, which are the same underlying problem behind heart disease, reduce the blood flow needed for a firm erection. In fact, ED often appears 2 to 5 years before men experience heart attacks, making it one of the earliest warning signs of cardiovascular trouble. If you’re dealing with new or worsening ED, it’s worth getting your heart health checked, not just your sexual function.

Lifestyle Changes That Make a Real Difference

Exercise is one of the most effective non-drug interventions for ED. Men who did aerobic activity like walking, running, or cycling for 30 to 60 minutes, three to five times a week, saw meaningful improvement in erectile function compared to men who stayed sedentary. The effect isn’t subtle. Harvard Health has reported that regular aerobic exercise may work about as well as medication for some men.

The reason is straightforward: exercise improves the health of your blood vessels, lowers blood pressure, reduces inflammation, and helps your body produce the chemical signals that trigger erections. It also reduces belly fat, which matters because excess body fat converts testosterone into estrogen and contributes to the vascular problems that cause ED in the first place.

Other changes that support erectile function include quitting smoking (which directly damages blood vessel lining), reducing alcohol intake, improving sleep quality, and managing conditions like diabetes and high blood pressure that accelerate vascular damage.

Oral Medications

PDE5 inhibitors are the first-line medical treatment for ED. They work by blocking the enzyme that breaks down cGMP, allowing blood to flow into the penis more easily and stay there longer during arousal. These medications don’t create an erection on their own. You still need sexual stimulation for them to work.

The three most commonly prescribed options differ mainly in timing. Sildenafil starts at 50 mg and should be taken about 60 minutes before sex. Vardenafil starts at 10 mg with a similar 60-minute lead time. Tadalafil also starts at 10 mg but lasts significantly longer, up to 36 hours, which gives more flexibility around timing. Tadalafil can also be taken daily at a lower dose so you don’t have to plan around it.

These medications are effective for most men, but they work best when the underlying blood vessel function isn’t severely compromised. Men with poorly controlled diabetes, significant nerve damage, or advanced cardiovascular disease may see less benefit.

When the Cause Is Psychological

Performance anxiety is one of the most common drivers of ED in younger men, and it creates a vicious cycle: one episode of difficulty leads to worry, which causes more difficulty, which deepens the worry. The body’s stress response actively works against erections by constricting blood vessels and diverting blood away from non-essential functions.

Cognitive behavioral therapy breaks this cycle by helping you identify the automatic thoughts that hijack your arousal, things like “this will happen again” or “something is wrong with me.” A therapist helps you examine whether those beliefs are actually supported by evidence, then replace them with more realistic ones like “my body responds when I’m relaxed.” Most men see meaningful change within 8 to 12 weeks, though lasting confidence typically develops over several months as new patterns become second nature.

Some practical strategies work immediately. Breathing exercises before intimacy, like inhaling for four counts, holding for seven, and exhaling for eight, slow your heart rate and signal safety to your nervous system. Shifting your focus from performance to sensation (noticing warmth, touch, and closeness rather than monitoring whether you’re hard enough) reduces the mental pressure that kills arousal. Many men find that temporarily removing the expectation of intercourse entirely, and simply exploring closeness and touch, allows the body to relax and arousal to return naturally.

Checking Your Testosterone

Low testosterone contributes to ED in some men, particularly when it’s accompanied by fatigue, reduced sex drive, loss of muscle mass, or mood changes. The American Urological Association defines low testosterone as a total level consistently below 300 ng/dL, measured on at least two early-morning blood draws. Morning matters because testosterone levels naturally peak in the early hours and drop throughout the day.

If your levels fall below that threshold and you have symptoms, testosterone replacement can improve desire and, in some cases, erectile function. But testosterone alone doesn’t fix ED caused by blood vessel problems, so it’s often used alongside other treatments rather than as a standalone solution.

Options When Medications Don’t Work

About 30% of men don’t respond well to oral medications. For them, several second-line treatments exist.

Penile injections use a medication called alprostadil, delivered directly into the side of the penis with a very small needle before sex. This bypasses the need for nerve signaling entirely and produces an erection within minutes. The success rate is around 80%, making it one of the most reliable options available. The main risks include prolonged erection requiring medical attention (about 4% of cases) and scar tissue formation at the injection site (about 8%). Most men who try it say the injection is less painful than they expected.

Vacuum erection devices are non-invasive and drug-free. A plastic cylinder placed over the penis creates suction that draws blood in, and a constriction ring at the base holds it there. They look awkward, but they work. Long-term studies show patient satisfaction rates around 84% and partner satisfaction around 89%. They’re particularly useful for men who can’t take medications due to heart conditions or drug interactions.

Penile implants are a surgical option reserved for men who haven’t had success with other treatments. A device is placed inside the penis that can be inflated when needed. Satisfaction rates are high, but the procedure is permanent and irreversible.

Supplements: What Actually Works

L-citrulline is the supplement with the most evidence behind it for ED. Your body converts it into L-arginine, which is then used to produce nitric oxide, the same chemical signal that starts the erection process. Clinical evidence suggests it can ease symptoms of mild to moderate ED, though it doesn’t work as well as prescription medications. Doses up to 6 grams per day have been used in studies, but no optimal dose has been established.

Most other supplements marketed for ED, including horny goat weed, maca root, and ginseng, have limited or inconsistent evidence. They’re unlikely to cause harm at standard doses, but they’re also unlikely to produce the kind of results you’d notice if your ED is more than very mild.