What to Do If You Test Positive for HPV

A positive HPV test is not a cancer diagnosis. Most HPV infections clear on their own, and even the highest-risk strains are manageable with proper follow-up. What happens next depends on which HPV type you tested positive for and whether your Pap test showed abnormal cells. Here’s a practical breakdown of what to expect.

Your Next Steps Depend on the HPV Type

HPV screening tests check for 14 cancer-causing (oncogenic) strains, and many also identify whether you have type 16 or 18 specifically. This distinction matters because it determines how quickly your provider will want to investigate further.

HPV 16 is the highest-risk type. If your test is positive for type 16 or 18, a colposcopy (a closer look at your cervix with a magnifying instrument) is recommended regardless of what your Pap test shows. HPV 18 has a particularly strong association with a type of cervical cancer called adenocarcinoma, so providers take it seriously even when the Pap results look completely normal.

If your positive result is for one of the other 12 high-risk types and your Pap test is normal, the standard recommendation is simply to come back in one year for repeat testing. No immediate procedures are needed. Many of these infections will resolve on their own by that follow-up visit.

What Happens During a Colposcopy

A colposcopy is an office procedure, not surgery. Your provider uses a speculum (the same instrument used during a Pap test) and a magnifying device to examine your cervix closely. They’ll apply a vinegar or iodine solution to the cervix, which washes away mucus and causes abnormal areas to stand out visually. The whole process takes about 15 to 20 minutes.

Your provider is looking for specific signs: whitish patches on the cervix, unusual blood vessel patterns, or areas that appear swollen or worn down. If anything looks abnormal, they’ll take a small tissue sample (biopsy) from that spot. The biopsy pinches briefly but is over in seconds. Results typically come back within one to two weeks and tell your provider whether the cells are precancerous or just mildly abnormal.

If You Need a LEEP Procedure

If your biopsy shows high-grade precancerous changes, your provider will likely recommend a LEEP (loop electrosurgical excision procedure). This removes the abnormal tissue from the surface of your cervix using a thin wire loop that carries an electrical current. In cases where the Pap already showed high-grade changes and the HPV type is 16, a LEEP can be done right away without waiting for a colposcopy biopsy first.

The procedure itself takes about 20 minutes under local anesthesia. You can go back to work or school within a day or two. Mild cramping is common for a few days, and you’ll notice vaginal discharge and spotting for one to three weeks. Plan on avoiding baths, swimming, exercise, and intercourse for about four weeks while your cervix heals. Full recovery takes four to six weeks.

Most HPV Infections Clear Without Treatment

Your immune system is the primary tool for eliminating HPV. Even for the highest-risk strains, the body clears the majority of infections within a couple of years. In a large vaccine trial that tracked women ages 18 to 25, about 69% of HPV 16 infections cleared within two years, and 85% of HPV 18 infections cleared in the same timeframe. By four years, clearance rates reached 82% for HPV 16 and 90% for HPV 18.

This is why “watchful waiting” with repeat testing is the standard approach for many positive results. The goal of screening isn’t to treat every infection. It’s to catch the small percentage that persist and develop precancerous changes before they become dangerous.

Smoking Makes HPV Harder to Clear

If you smoke, this is one of the most concrete reasons to quit. Smoking suppresses the local immune response in cervical tissue, making it harder for your body to fight off an HPV infection. It enhances the persistence of high-risk HPV strains and promotes the kind of cellular damage that pushes infections toward precancerous changes. The connection is well established: smoking is one of the major modifiable risk factors for cervical cancer progression in HPV-positive individuals.

Vaccination Still Helps After a Positive Test

Getting the HPV vaccine after you’ve already tested positive is still worthwhile. The nine-strain vaccine protects against multiple HPV types, and testing positive for one strain doesn’t mean you’ve been exposed to all of them.

There’s also growing evidence that vaccination benefits people with existing infections. In a study of 320 HPV-positive women, those who received the vaccine had significantly higher rates of HPV disappearance: 72.4% of vaccinated women cleared their infection completely, compared to 45.7% of unvaccinated women. The effect was strongest for strains covered by the vaccine. Among women who had both a LEEP procedure and vaccination, 81.1% achieved a negative HPV result, compared to just 34.3% of women who had neither intervention.

Condoms Reduce but Don’t Eliminate Transmission

HPV spreads through skin-to-skin contact, not just through fluids, so condoms don’t provide complete protection. However, they make a meaningful difference. In a study of men, consistent condom use cut the risk of acquiring HPV roughly in half compared to never using condoms. Consistent condom users also cleared oncogenic HPV infections about 30% faster than those who never used condoms.

You don’t need to disclose HPV status the way you would for other STIs. HPV is extraordinarily common, most sexually active people contract it at some point, and there is no approved HPV test for men. That said, using condoms consistently does reduce the viral load passed between partners and helps both of you clear infections more efficiently.

HPV and Pregnancy

A positive HPV test does not prevent you from having a healthy pregnancy. Prenatal care will typically include monitoring your cervical health, but invasive procedures like LEEP are generally postponed until after delivery unless there’s a concern about cancer rather than precancer.

Vaginal delivery does carry a higher chance of passing HPV to the newborn compared to cesarean delivery. One study found HPV detection rates of 28.2% in vaginally delivered infants versus 14.9% in those born by cesarean. The transmission appears to happen primarily during passage through the birth canal rather than through the amniotic fluid. However, HPV detected in newborns often clears on its own, and routine cesarean delivery is not recommended solely because of a positive HPV test. Your provider will weigh this alongside other factors specific to your pregnancy.

Genital Warts Are a Separate Issue

If your HPV diagnosis involves visible genital warts rather than a high-risk screening result, you’re dealing with low-risk HPV strains (most commonly types 6 and 11). These types don’t cause cancer, but the warts themselves can be uncomfortable and persistent.

Several treatment options exist. You can apply prescription creams or gels at home: imiquimod cream (applied three times per week for up to 16 weeks), podofilox solution (applied twice daily for three days on, four days off, for up to four cycles), or sinecatechins ointment, a green tea extract applied three times daily until warts clear. Your provider can also remove warts in-office using cryotherapy (freezing with liquid nitrogen), surgical excision, or a chemical acid solution. Warts can recur after any treatment, so follow-up visits are important.