Platelet-Rich Plasma (PRP) therapy is a regenerative treatment utilizing the body’s own healing factors to address musculoskeletal issues. The process involves drawing a small blood sample, concentrating the platelets, and injecting the solution into the damaged area, such as the hip joint. These concentrated platelets release growth factors and proteins that stimulate cell repair and tissue regeneration. Understanding the necessary post-injection care and recovery timeline is important for maximizing the treatment’s effectiveness in the hip. This guide outlines the phases of recovery and specific aftercare protocols.
Immediate Post-Injection Experience and Care
The body initiates its healing cascade during the first 24 to 72 hours following the injection. Temporary localized symptoms, including mild to moderate pain, stiffness, and warmth, are normal around the injection site. This discomfort indicates that the concentrated platelets are actively beginning the inflammatory phase of tissue repair.
Initial care focuses on protecting the site and managing early movement. Physicians typically recommend resting for the first 24 to 48 hours, but complete immobility should be avoided. Light movement and gentle range-of-motion exercises are encouraged to prevent stiffness and promote circulation. If the hip joint was injected, a cane or crutch may be recommended briefly to limit full weight-bearing.
Keep the injection site clean and dry for the first day, avoiding baths or swimming until it has fully healed. Avoid applying excessive pressure or massaging the area, as this can displace the concentrated plasma. Report any symptoms that intensify significantly or persist beyond a few days to the healthcare provider.
Managing Pain and Inflammation
The body’s initial inflammatory response is necessary for the PRP healing process, signaling the start of tissue regeneration. Therefore, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), such as ibuprofen or naproxen, must be avoided. These medications inhibit cyclooxygenase (COX) enzymes, suppressing the inflammation needed to activate platelets and release growth factors. Taking NSAIDs compromises platelet function and significantly reduces the therapeutic benefit of the injection.
Patients are typically instructed to avoid all NSAIDs for one to four weeks after the procedure. For pain relief, Acetaminophen (Tylenol) is the recommended alternative, as it manages pain without interfering with platelet activity.
Non-pharmacological methods also help manage discomfort. Applying ice intermittently for short intervals can soothe the area. However, some protocols advise against applying ice or heat in the first 72 hours to prevent temperature extremes from interfering with the local biological response. Following the specific icing protocol provided by the physician is important.
Activity Restrictions and Rehabilitation Timeline
Recovery from a hip PRP injection follows a structured, multi-phase progression to prevent overstressing the healing tissue. The timeline is flexible, depending on the patient’s progress and the injury treated. Physical therapy throughout these phases is essential to safely regain strength, flexibility, and function, supporting the long-term effectiveness of the treatment.
The rehabilitation process is generally divided into four phases:
- Phase 1: Initial Rest (First week). This requires limited weight-bearing and avoidance of strenuous activity, high-impact movements, or heavy lifting to allow the treatment to settle.
- Phase 2: Light Activity (Weeks 2 through 4). This allows for the introduction of passive movement, including gentle walking, light stretching, and non-weight-bearing exercises like using a stationary bike. Formal physical therapy is often paused for the first two weeks.
- Phase 3: Active Rehabilitation and Strengthening (Weeks 4 through 8). The goal is to gradually rebuild strength and function in the hip joint and surrounding musculature with guidance from a physical therapist. Exercises should focus on minimal compressive loading, and activity should be limited to about half of the usual capacity.
- Phase 4: Return to Sport or Full Activity (After eight weeks). This phase begins once the physician provides clearance.
Timeline for Therapeutic Results
The therapeutic benefits of a hip PRP injection are not immediate, as the treatment stimulates gradual tissue regeneration. The healing process unfolds over several weeks and months as growth factors promote new tissue formation. Patients often notice subtle improvements in pain and mobility within the first four to six weeks.
The most noticeable improvements in comfort and function typically occur around two to three months after the injection. Peak results are generally achieved between three and six months, reflecting the slow biological process of building new, healthy tissue. Follow-up appointments track progress, and a second injection may be considered if the response is not satisfactory after three months.

