What to Take for Diarrhea: OTC Meds and Home Remedies

For most cases of acute diarrhea, an over-the-counter medication like loperamide (Imodium) or bismuth subsalicylate (Pepto-Bismol) will provide relief within hours. But what you drink matters just as much as what you take. Staying hydrated is the single most important thing you can do, since diarrhea pulls water and electrolytes out of your body fast.

Over-the-Counter Medications

Loperamide is the most widely used anti-diarrheal medication. It works by slowing down the movement of your intestines, giving your body more time to absorb water from food. The standard approach for adults is to take two caplets after the first loose bowel movement, then one caplet after each subsequent loose stool. Don’t exceed 8 caplets in 24 hours with the over-the-counter version.

Bismuth subsalicylate is a good alternative, especially if you also have nausea or an upset stomach. It can turn your tongue dark and your stool grayish black, which looks alarming but is harmless and goes away once you stop taking it. Persistent ringing in the ears is a side effect that warrants stopping the medication.

One important safety note: bismuth subsalicylate is related to aspirin. Children and teenagers should not take it during or after a viral illness like the flu or chickenpox because of the risk of Reye’s syndrome, a rare but serious condition. Anyone with an aspirin allergy should also avoid it.

Hydration Comes First

Even if you can’t eat, you need to keep drinking. Take small sips of water or suck on ice chips. Broth, popsicles, diluted fruit juice (half water, half juice), and weak decaffeinated tea all work well. The goal is steady, small amounts rather than gulping down a full glass, which can trigger more cramping.

If you’re showing signs of dehydration (dry mouth, dizziness when standing, dark or infrequent urine), an oral rehydration solution like Pedialyte is more effective than a sports drink. You can also make your own: mix 4 cups of water with half a teaspoon of salt and 2 tablespoons of sugar. This combination helps your intestines absorb fluid more efficiently than plain water.

What to Eat (and What to Skip)

The old BRAT diet (bananas, rice, applesauce, toast) is fine for a day or two, but you don’t need to limit yourself to just those four foods. Brothy soups, oatmeal, boiled potatoes, crackers, and unsweetened dry cereals are all easy on your stomach. Once things settle, add in more nutritious options like cooked carrots, sweet potatoes without skin, avocado, skinless chicken or turkey, fish, and eggs.

What you avoid matters as much as what you eat. Several common foods and drinks actively make diarrhea worse:

  • Caffeine from coffee, tea, cola, and chocolate speeds up your gut and can increase loose stools
  • Dairy products like milk, cheese, and ice cream are harder to digest when your gut is inflamed
  • Fried and fatty foods are difficult for a stressed digestive system to process
  • Sugar alcohols like sorbitol and xylitol, found in sugar-free gum and candies, can cause diarrhea on their own
  • High-fructose foods including soft drinks, apples, pears, and dried fruits can pull water into the intestines
  • Spicy and acidic foods like citrus, tomato sauces, and vinegar-based dressings irritate the gut lining
  • Insoluble fiber from raw leafy greens, fruit skins, popcorn, nuts, seeds, and beans
  • Alcohol and carbonated drinks

Probiotics Can Shorten Recovery

Certain probiotic strains have solid evidence behind them for acute diarrhea. Two stand out: Lactobacillus rhamnosus GG (often labeled LGG) and Saccharomyces boulardii, a beneficial yeast. Both have been shown across multiple clinical trials to reduce the duration of infectious diarrhea by roughly one day. Look for products containing at least 10 billion CFU (colony-forming units) daily, taken for 5 to 10 days.

Probiotics aren’t a replacement for hydration or medication, but they can be a useful addition, especially for stomach bugs and traveler’s diarrhea.

Stomach Bug vs. Food Poisoning

Knowing the cause can help you estimate how long you’ll be dealing with symptoms. Food poisoning tends to hit fast, usually 2 to 6 hours after eating contaminated food, and often resolves quickly. A stomach bug (viral gastroenteritis) has a longer incubation period of 24 to 48 hours, typically lasts about two days, and is more likely to come with fever and chills. Stomach bugs spread through contact with infected people or contaminated surfaces, while food poisoning comes from improperly cooked or stored food.

In either case, the treatment is the same: fluids, bland food, and over-the-counter medication if needed.

Warning Signs That Need Medical Attention

Most diarrhea resolves on its own within a few days. But certain symptoms signal something more serious. Seek medical care if you experience bloody stool, a fever above 102°F, diarrhea lasting more than 3 days, vomiting so severe you can’t keep liquids down, or signs of dehydration like dizziness, dry mouth, and very little urine output. Pregnant women with fever and flu-like symptoms should also contact their doctor promptly.