What Vitamin Deficiency Causes Cracked Mouth Corners?

Angular cheilitis is the medical term for cracked mouth corners, an inflammatory condition occurring at the angles where the upper and lower lips meet (labial commissures). It typically presents with redness, swelling, and painful cracks or fissures that may crust over. While many factors cause this localized skin breakdown, a deficiency in certain micronutrients is an often-overlooked source. Understanding these specific nutritional deficits is key to effective resolution.

The Role of B Vitamins and Minerals in Skin Health

The most frequently cited nutritional cause is a deficiency of Riboflavin (Vitamin B2). Riboflavin is integral to cellular growth and function, acting as a precursor for coenzymes in energy metabolism. A lack of this vitamin directly impairs the maintenance and repair of mucosal membranes, including the delicate skin at the mouth’s angles, leading to inflammation and breakdown. This specific deficiency is sometimes called cheilitis ariboflavinus.

Several other micronutrients also contribute to the health of epithelial tissues. Deficiencies in Pyridoxine (Vitamin B6) and Niacin (Vitamin B3) compromise the body’s ability to repair damaged tissue and maintain a healthy skin barrier. Folate and Vitamin B12 deficiencies can also contribute to these symptoms.

Mineral shortfalls like Iron and Zinc have also been linked to angular cheilitis. Iron is necessary for red blood cell production; its deficiency can cause anemia, reducing the oxygen delivery needed for tissue repair. Zinc plays a direct role in immune function and wound healing, slowing the skin’s ability to mend cracks.

Recognizing Non-Nutritional Triggers

Many cases of angular cheilitis are not primarily caused by dietary deficiencies, even though nutritional status is a factor. Common non-nutritional triggers are localized factors that create a chronic, moist environment at the mouth angles. The pooling of saliva in the creases, often due to chronic lip licking, drooling, or poorly fitting dental appliances, causes the skin to become macerated.

When this constant moisture evaporates, it leads to dryness and cracking, encouraging the growth of infectious organisms. The most common infectious agent is the fungus Candida albicans (the yeast that causes thrush), but bacteria like Staphylococcus aureus can also colonize the compromised skin.

In the elderly, the loss of vertical dimension in the face, often caused by severe tooth wear or ill-fitting dentures, creates deeper folds where saliva collects. This mechanical issue, combined with the normal aging process that reduces skin elasticity, increases susceptibility to irritation. Contact dermatitis from topical irritants, such as ingredients in toothpaste, cosmetics, or chewing gum, can also initiate inflammation.

Dietary Solutions and Prevention Strategies

Addressing a nutritional cause begins with consuming a diet rich in the implicated vitamins and minerals. To boost Riboflavin (B2) intake, focus on foods such as dairy products (milk and yogurt), lean meats, eggs, and fortified cereals. Incorporating these sources helps maintain mucosal tissue.

To increase Iron and Zinc, which support immune response and tissue repair, consume more red meat, poultry, and beans. Oysters and pumpkin seeds are dense sources of Zinc, and fortified grain products contribute to Iron intake. Proper hydration is also helpful, as dehydration can exacerbate lip dryness and chapping.

If a nutritional deficit is suspected, a balanced diet is the first step toward resolution. Before starting high-dose supplementation, consult a healthcare professional, as excessive intake of some micronutrients can be harmful. If the cracked mouth corners persist for more than a few weeks despite dietary changes, or if signs of a worsening infection (such as significant pain or spreading redness) are present, a medical evaluation is necessary.