Testosterone cream is a specialized hormone therapy addressing symptoms of low testosterone, often prescribed for postmenopausal women with hypoactive sexual desire disorder. Although women naturally produce testosterone, levels can decline with age or after surgical menopause. This treatment is typically administered as a transdermal cream or gel designed for systemic absorption into the bloodstream. Because testosterone is a regulated substance, its use requires a valid prescription from a licensed medical professional and ongoing supervision.
Specific Application Sites and Technique
For the cream to work effectively and safely, it must be applied to areas of the body that facilitate consistent, systemic absorption into the circulation. Recommended sites include non-hairy areas with relatively thin skin and good blood flow, such as the inner thigh, the upper arm, the lower abdomen, or the back of the calf. Applying the cream to these locations ensures the testosterone enters the system to exert its effects on tissues like the brain, bone, and muscle.
The technique is crucial; the skin must be clean and completely dry before application. Dispense the exact, prescribed dose onto your finger or a measuring device. Gently rub the cream onto the chosen area until it is fully absorbed, ensuring the medication disappears into the skin’s surface. After application, allow the area to air dry completely for several minutes before covering it with clothing.
To prevent skin irritation, rotate the application site daily, such as alternating between the left and right inner thigh. Some compounded formulations may be prescribed for localized application directly to the vulvar or clitoral area for specific symptoms. This distinct method often results in higher local concentrations and should only be done if explicitly instructed by your clinician. Systemic absorption sites are generally favored to achieve a more stable hormone level in the blood.
Dosage and Product Safety Considerations
The dosage of testosterone cream for women is highly specific, aiming for a concentration within the normal premenopausal female physiologic range. A typical starting dose is about 5 milligrams (mg) of testosterone daily, which is significantly lower than the dose prescribed for men. Many products are formulated by compounding pharmacies to ensure this precise, low dosing. They often include specialized measuring devices, such as a syringe or pump, which must be used to measure the exact amount prescribed.
A major safety consideration is preventing the accidental transfer of the cream to others, including partners, children, or pets. Testosterone can be absorbed through skin-to-skin contact, potentially causing hormonal changes. To mitigate this risk, wash your hands thoroughly with soap and water immediately after application. Ensure the application site is completely dry before close contact, and cover the area with clothing for a few hours afterward.
Storage of the product requires care due to its status as a controlled substance. The cream should be kept securely out of the reach of children. Store it according to the pharmacist’s instructions, typically at room temperature and away from excessive heat or moisture. Adhering to these safety protocols is important for both your health and the health of those you live with.
Navigating Prescription and Medical Oversight
Obtaining testosterone cream requires a full medical evaluation and a prescription because it is a regulated substance. A healthcare provider must first confirm that the symptoms warrant treatment, often by taking a detailed medical history and performing baseline hormone level testing. Since there is no FDA-approved testosterone product specifically designed for women in the United States, your prescription will likely be for a compounded cream or a reduced dose of a product approved for men. Both options necessitate the guidance of a specialist.
Ongoing medical oversight is a necessary component of this therapy to ensure safety and effectiveness. This involves regular blood testing to monitor total testosterone and Sex Hormone Binding Globulin (SHBG) levels. Initial blood work is typically performed a few weeks after starting the cream, and then every few months once the dosage is stable. The primary goal of this monitoring is to confirm that the testosterone level remains within the premenopausal female range, preventing the dose from becoming too high.
If the dose exceeds the appropriate physiologic range, you may experience virilization symptoms, which are signs of androgen excess. These side effects can include acne, hirsutism (increased body or facial hair growth), and, in rare but serious cases, deepening of the voice or clitoral enlargement. Consulting with a physician familiar with hormone therapy, such as an endocrinologist or gynecologist, ensures the regimen is tailored to your body’s needs, minimizing risks while maximizing therapeutic benefits.

