The iliac veins are large blood vessels situated deep within the pelvis and lower abdomen, playing a fundamental role in the circulatory system. Their primary function is to collect deoxygenated blood from the lower extremities and pelvic organs, channeling it back toward the heart for re-oxygenation. Understanding the location and structure of these major veins provides insight into a significant pathway for blood return, necessary for maintaining vascular health. Issues within the iliac vein system can have serious implications for blood flow throughout the lower half of the body.
Defining the Three Iliac Veins
The term “iliac vein” refers to a pair of large veins on both the right and left sides of the body, categorized into three segments: the External, Internal, and Common iliac veins. These vessels are located within the deep pelvis, forming a crucial network for venous return. The system begins with the External Iliac Vein, which is the continuation of the femoral vein from the thigh.
The External Iliac Vein passes under the inguinal ligament, ascending along the inner side of the corresponding external iliac artery, tracking along the rim of the pelvic bone. The Internal Iliac Vein originates near the greater sciatic foramen and remains deep within the pelvic cavity.
The Internal Iliac Vein follows a path anterior to the sacroiliac joint, draining the pelvic organs and walls. The Common Iliac Vein is formed where the External and Internal iliac veins merge, typically in front of the sacroiliac joint. This Common Iliac Vein is the shortest segment and ascends toward the midline of the lower abdomen, running deep alongside the lumbar vertebrae.
The Role of Iliac Veins in Drainage
The iliac vein system functions as the main conduit for collecting deoxygenated blood from the entire lower half of the body. Each segment is responsible for draining specific regions. The External Iliac Vein collects blood from the lower limbs, continuing the flow from the femoral vein.
It also receives blood from tributaries draining the lower anterior abdominal wall and the adjacent iliac region, including the inferior epigastric vein and the deep circumflex iliac vein. Its role focuses on the muscular and skeletal structures of the lower body and the abdominal periphery.
The Internal Iliac Vein drains the organs and structures within the pelvic cavity. This includes blood from the pelvic walls, the gluteal region, and the perineum. Specific sources are veins draining the bladder, rectum, reproductive organs, and the superior and inferior gluteal veins.
The Common Iliac Vein acts as a central collector, accepting all the blood volume gathered by the External and Internal iliac veins on its side. It combines these two major streams, preparing the blood for the final return journey to the heart.
Forming the Inferior Vena Cava
The final destination for the blood collected by the iliac system is the Inferior Vena Cava (IVC), the largest vein in the human body. This formation occurs when the right and left Common Iliac Veins join together in the lower abdomen, typically near the fifth lumbar vertebra (L5 vertebral level).
Once the two Common Iliac Veins unite, they form the IVC, which ascends through the abdomen and chest. The IVC runs along the right side of the vertebral column, situated retroperitoneal (behind the abdominal cavity lining). This single, massive vessel delivers all the blood from the lower body directly into the right atrium of the heart.
The IVC’s large diameter and strategic location allow it to handle the significant volume of blood collected. This junction marks where the iliac venous system ends and the main trunk of the body’s venous return begins.
Clinical Significance of Iliac Vein Health
The size and location of the iliac veins make them susceptible to several serious health conditions, particularly those involving blood clots. Deep Vein Thrombosis (DVT) in the iliac veins is concerning because of the vessels’ proximity to the heart. A clot in this location, known as iliofemoral DVT, carries a high risk of breaking off and traveling to the lungs, causing a life-threatening Pulmonary Embolism.
Symptoms of iliac vein DVT often include sudden swelling and pain in the entire leg, and sometimes skin discoloration. Treating iliac vein clots is complex, frequently requiring clot-dissolving medications or mechanical removal. This prevents long-term damage to the vein valves and subsequent chronic venous insufficiency.
May-Thurner Syndrome
Another condition affecting these vessels is May-Thurner Syndrome, also known as Iliac Vein Compression Syndrome. This anatomical variation occurs when the right common iliac artery crosses over and compresses the left common iliac vein against the lumbar spine. This chronic compression can cause scarring and fibrous spurs within the vein wall, reducing blood flow.
May-Thurner Syndrome is a cause of left-sided DVT and is more common in women. Symptoms include chronic leg swelling, pain, and sometimes varicose veins. The constant pressure leads to blood stasis, a major risk factor for clot formation. Diagnosis and treatment often involve imaging studies to confirm the compression and placement of a stent to keep the vein open.

