Waking up drenched in sweat or suddenly feeling overheated while recovering from a cold or flu can be alarming. This excessive perspiration, known medically as diaphoresis, is a common physiological event that signals a significant change in the body’s internal battle against infection. Feeling this intense heat and soaking through clothing is not a sign that the illness is worsening, but rather a direct result of the body’s temperature regulation system working to return to normal.
The Body’s Thermostat and Fever
The sensation of a fever begins with a signal that resets the body’s internal thermostat, located in the hypothalamus region of the brain. When a virus or bacteria enters the body, immune cells respond by releasing fever-inducing substances called endogenous pyrogens. These chemical messengers, which include cytokines, travel through the bloodstream to the brain’s thermoregulatory center.
Once they reach the hypothalamus, these pyrogens trigger the synthesis of prostaglandin E2. This specific prostaglandin acts directly to raise the temperature set point, essentially telling the body that the normal 98.6°F (37°C) is now too cold. The body then works to match this new, higher set point, which is why a person experiences cold sensations and shivers. Shivering is a mechanism of heat production, and peripheral blood vessels constrict to conserve heat internally, marking the initial rising phase of the fever.
Sweating as the Body’s Cooling System
The profuse sweating that often follows a fever is a direct indication that the hypothalamic set point has been successfully lowered back to its normal level. This shift occurs because the immune system has cleared enough of the pathogen to stop the release of pyrogens, or because fever-reducing medications have inhibited the production of prostaglandin E2. The body is now in a state where its core temperature is significantly higher than the new, lower set point.
To rapidly shed this excess heat, the body activates its cooling mechanisms. The first is peripheral vasodilation, where blood vessels near the skin’s surface widen to bring warm blood closer to the exterior, allowing heat to dissipate into the environment. The second mechanism is diaphoresis, or massive sweating. The liquid secreted by the millions of sweat glands on the skin absorbs heat as it evaporates.
This process of evaporative cooling is highly efficient, but it requires a large volume of water to transfer the heat away from the body. Because the body is attempting to cool down quickly from a higher temperature, the resulting sweat production is often so heavy that it leads to soaking through clothing and bedding. The intense, damp sweating is a sign of the body’s recovery phase, where the fever has been broken and the core temperature is stabilizing.
Managing and Recovering from Excessive Sweating
The primary concern when experiencing excessive sweating is the rapid loss of fluids and electrolytes, which can lead to dehydration. It is important to prioritize the intake of water, clear broths, and electrolyte-rich beverages to replenish the sodium and potassium lost in the perspiration. Replacing these fluids helps the body maintain its circulatory function and supports the ongoing recovery process.
Damp clothing and bedding should be changed immediately after sweating to prevent the body from becoming chilled. When the skin is wet, evaporation of moisture can cause the core temperature to drop too far, leading to uncomfortable cold sensations. Wearing light, breathable layers of clothing, such as cotton, can help manage the temperature fluctuations and allow moisture to wick away more easily. Avoid the impulse to bundle up with heavy blankets, as this can trap heat and trigger further sweating, worsening the cycle of fluid loss and discomfort.

