Why Are My Gums Peeling? Causes and When to Worry

When the delicate tissue lining the gums appears to peel away, it causes immediate concern. This process, known clinically as epithelial sloughing or gingival desquamation, involves the shedding of the protective outer layer of the gum tissue. It signals that the oral environment or the body’s internal health is experiencing a reaction or imbalance. Understanding the difference between this tissue breakdown and other common gum issues is the first step toward finding a solution. This article will identify the common external triggers and the rarer, more serious systemic causes of this uncomfortable symptom.

What Exactly is Gum Sloughing?

True gum sloughing is characterized by the superficial layer of the oral mucosa separating from the underlying tissue. This often presents as thin, white or gray sheets of tissue that peel away easily, sometimes spontaneously or during brushing. The tissue underneath is left raw, intensely red, and extremely tender, leading to a burning sensation and discomfort. This phenomenon is distinct from common gum recession, which involves the gum line pulling back slowly and exposing the tooth root. Sloughing is an active, widespread shedding event that often affects large areas of the gums, inner cheeks, and lips simultaneously.

Everyday Causes of Peeling Gums

The most frequent causes of gum sloughing are irritations from products used daily in the mouth, which contact the oral mucosa. Sodium Lauryl Sulfate (SLS), a common detergent and foaming agent found in many toothpastes, is a primary culprit. As an anionic surfactant, SLS can disrupt the protective mucosal barrier and denature proteins, leading to shedding of the epithelial layer. Concentrations of SLS as low as 0.5% to 1.5% have been demonstrated to cause desquamation in sensitive individuals.

Chemical or thermal burns can also induce tissue separation. Direct exposure to acidic substances, such as placing an aspirin tablet against the gum for pain relief, causes chemical necrosis and subsequent sloughing. Similarly, high-concentration whitening agents, particularly if they leak from trays, can chemically burn the gums. Extreme temperatures from very hot foods or liquids cause thermal injury, leading to the rapid shedding of the outer epithelial layer.

Certain oral hygiene products contain strong ingredients like alcohol, which can dry out and irritate the mucosal tissues. This chronic irritation can weaken the epithelial surface, making it more prone to shedding. Some medications taken systemically may also have side effects that manifest as oral irritation or mucositis. Drug classes like Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) and certain cardiovascular drugs, such as ACE inhibitors, can cause nonspecific ulceration and sloughing as a hypersensitivity reaction.

Systemic Conditions That Affect Gum Tissue

When topical irritants are ruled out, gum sloughing can be a manifestation of a deeper, systemic health issue. The specific presentation of sloughing, redness, and erosion is often categorized by health professionals as desquamative gingivitis. This condition is frequently linked to autoimmune disorders, where the body’s immune system mistakenly attacks its own oral tissue.

Pemphigus Vulgaris and Mucous Membrane Pemphigoid are two such disorders, involving a faulty immune response against the proteins that anchor tissue layers together. In these cases, the gums develop fragile blisters that quickly rupture, causing widespread, painful erosions and subsequent sloughing. Erosive Lichen Planus is another inflammatory condition that can affect the gums, leading to painful, lacy white patches alongside areas of significant redness and erosion.

Systemic infections and nutritional deficiencies can also impact the integrity of the gum tissue. Oral candidiasis (thrush) is a fungal infection that can present with white, scrapable plaques that may mimic sloughing. Deficiencies in certain B vitamins, notably B12 and folate, disrupt the regeneration of mucosal cells. This results in mucosal atrophy and inflammation, making the gum lining fragile and susceptible to breakdown.

When to Seek Professional Diagnosis and Care

If gum sloughing is occurring, the first step is to immediately remove potential topical irritants, such as switching to an SLS-free and alcohol-free toothpaste and mouthwash. Immediate measures for relief include gentle rinsing with warm salt water to soothe the raw tissue. However, if the symptoms persist for more than a week, cause severe pain, or interfere with eating and drinking, professional diagnosis is mandatory.

A dental professional or oral pathologist will conduct a thorough examination and review your full medical and product history. If an autoimmune cause is suspected, the diagnostic process may involve a small tissue sample, or biopsy, to examine the cellular layers and identify the presence of specific autoantibodies. For topical reactions, patch testing may be necessary to pinpoint a specific chemical allergen.

Depending on the cause, treatment can range from simple product substitution to prescription medications. Autoimmune or inflammatory conditions often require the use of topical corticosteroids to reduce the immune response and promote healing of the gum tissue. Early and accurate diagnosis is the most effective way to manage the underlying condition and prevent long-term damage to the oral mucosa.