Pain under the right rib cage, known medically as the Right Upper Quadrant (RUQ), is a common complaint with a wide range of potential origins. This complex area houses numerous organs and musculoskeletal structures, meaning discomfort can vary significantly from simple, self-limiting issues to serious conditions requiring prompt medical care. The characteristics of the pain—sharp, dull, constant, or intermittent—often provide the first clues regarding its source. This article serves as an informational guide to possible causes, but it is not a substitute for professional medical diagnosis. Any persistent or severe pain should be evaluated by a healthcare professional.
Key Organs Located Under the Right Rib Cage
The location of the pain corresponds directly to the organs nestled beneath the bony protection of the lower right ribs. The largest structure here is the liver, which occupies most of the RUQ, sitting just below the diaphragm. Tucked beneath the liver is the gallbladder, a small, pear-shaped organ responsible for storing and concentrating bile. The right kidney is positioned toward the back of the abdomen, often extending high enough to be considered part of the RUQ. Other structures include the hepatic flexure (the bend in the large intestine), the duodenum (the first part of the small intestine), and a portion of the pancreas.
Common Sources of Mild and Transient Discomfort
Not all discomfort in the RUQ signals a major organ problem, as many instances of pain are transient and benign. One frequent cause is trapped gas or general indigestion, often felt as a sharp, cramping sensation that shifts locations. This pain resolves as the gas moves through the digestive tract, particularly in the hepatic flexure of the colon. Musculoskeletal causes are common, often following physical exertion or injury. Straining the intercostal muscles between the ribs, or bruising a rib, causes localized tenderness that worsens with movement or deep breaths. Costochondritis, inflammation of the cartilage connecting the ribs to the breastbone, causes sharp, localized discomfort that intensifies with coughing or deep inhalation. These mild causes are generally characterized by pain that is fleeting, improves with rest, or responds readily to over-the-counter pain relievers.
Serious Conditions Requiring Medical Intervention
Gallbladder Disease
Persistent or recurrent pain under the right ribs often points to a pathological process within one of the underlying organs. Gallbladder issues are a frequent culprit. Gallstones cause intense, cramping pain known as biliary colic when they temporarily block a bile duct. This sharp discomfort often begins after eating a fatty meal, as the gallbladder contracts to release bile, and can radiate to the right shoulder blade or back. If a gallstone creates a sustained blockage, it can lead to cholecystitis, which is inflammation of the gallbladder wall. Cholecystitis causes constant, severe RUQ pain, accompanied by fever, nausea, and vomiting, requiring medical intervention.
Liver Conditions
Conditions affecting the liver, such as hepatitis (inflammation of the liver cells), can cause a dull, aching pain as the organ swells. Liver-related pain is often accompanied by systemic symptoms, including profound fatigue and jaundice, which is a yellowish discoloration of the skin and eyes. A liver abscess, a pus-filled pocket caused by bacterial infection, can also present with RUQ pain, along with high fever and chills.
Kidney Issues
Pain originating from the right kidney is often felt more in the flank or back, but it can radiate forward beneath the ribs. Kidney stones cause sudden, severe, wave-like pain as they move through the urinary tract. This pain is frequently associated with blood in the urine, painful urination, and nausea. Pyelonephritis, a serious bacterial infection of the kidney, presents with fever, back pain, and sometimes pain radiating to the RUQ, demanding immediate antibiotic treatment.
Gastrointestinal Causes
Gastrointestinal issues beyond simple gas can also localize pain in this quadrant. Duodenal ulcers, which are open sores in the lining of the first part of the small intestine, commonly cause a burning pain in the RUQ that may feel better or worse after eating. In addition, severe constipation can cause a backup of waste material, leading to distension and discomfort at the hepatic flexure of the colon.
When Pain Demands Immediate Medical Attention
Certain symptom combinations are considered “red flags” that indicate a potentially life-threatening situation and require an immediate visit to an emergency room. Any sudden onset of excruciating pain that makes a person double over, or pain that rapidly increases in intensity, warrants urgent evaluation. This kind of acute pain may signal a severe blockage, rupture, or acute infection.
Concerning symptoms that demand immediate medical attention include:
- Pain accompanied by a high fever and shaking chills, suggesting a serious infection such as acute cholecystitis or pyelonephritis, where prompt treatment is necessary to prevent sepsis.
- The appearance of jaundice (yellowing of the skin and the whites of the eyes) along with RUQ pain, indicating a severe problem with the liver or a complete blockage of the bile duct system.
- Vomiting blood or passing black, tarry stools, which can indicate internal bleeding from a peptic ulcer.
- Pain following a recent accident or trauma to the area, requiring immediate care to rule out internal injury or organ laceration.
When reporting symptoms to a medical professional, provide details about the pain’s duration, its severity on a scale of one to ten, and specific activities or foods that seem to make the discomfort better or worse.

