Continuous Positive Airway Pressure (CPAP) therapy is a widely used and highly effective treatment for obstructive sleep apnea, delivering pressurized air to keep the airway open during sleep. While CPAP often resolves morning headaches associated with low oxygen levels, the machine itself can inadvertently trigger new headaches. These headaches are typically not a sign of device malfunction, but rather an indication that a specific component of the therapy needs adjustment. Understanding these factors is the first step toward resolving this uncomfortable side effect and ensuring successful long-term therapy.
Incorrect Pressure Settings
The pressure setting on a CPAP machine is a fine balance; if it is too high or too low, it can lead to morning headaches. When the air pressure is set higher than necessary, it can force air into the stomach, a condition known as aerophagia. This air swallowing causes gas, bloating, and abdominal distension, which can result in referred pain perceived as a headache. High pressure can also create excessive force in the sinuses, leading to facial pressure or a sinus-type headache.
Conversely, a pressure setting that is too low fails to fully treat the underlying sleep apnea. Inadequate pressure allows for continued airway collapse, leading to repeated drops in blood oxygen saturation throughout the night. This intermittent nocturnal hypoxemia often manifests as a dull, generalized morning headache that resolves shortly after waking up. If you suspect your pressure is incorrect, contact your sleep physician or healthcare provider, as adjustments require a clinical assessment and must never be attempted without medical supervision.
Mask Fit and Seal Problems
The physical fit of the CPAP mask is a direct and common source of morning headaches, often presenting as a tension headache. An over-tightened headgear places sustained pressure on sensitive areas like the forehead or the bridge of the nose. This pressure can irritate the trigeminal and occipital nerves, causing an external compression headache—a dull ache that begins at the pressure point and spreads across the head. Tightening the straps to stop air leaks often causes this problem rather than solving it.
Air leaks themselves can also contribute to headache symptoms by blowing concentrated air directly into the eyes. This air leak can dry out the eyes and surrounding soft tissues, which is irritating enough to disrupt sleep and contribute to a headache. To troubleshoot, ensure the mask size is appropriate for your facial structure, as a poorly sized mask requires excessive tension to maintain a seal. Regularly inspecting the mask cushion for signs of wear is also helpful, since worn cushions require tighter straps to compensate for lost elasticity.
Dry Sinuses and Humidity Control
The constant stream of air delivered by the CPAP machine can be extremely drying to the delicate mucous membranes lining the nasal passages and sinuses. This drying effect, particularly when using unheated air, can lead to inflammation and irritation of the sinus tissues. The resulting congestion and inflammation can cause a sinus headache, characterized by pain and pressure around the eyes, cheeks, and forehead. This issue is often more pronounced in dry climates or during colder months when ambient air holds less moisture.
Most modern CPAP units include a heated humidifier to counteract this dryness by adding moisture to the airflow. Adjusting the humidifier’s temperature and moisture level is often the most effective solution for sinus discomfort. Using heated tubing can also prevent the humidified air from cooling down before it reaches the mask, helping maintain moisture and comfort. People who breathe through their mouth at night are especially prone to this dryness, as the air bypasses the natural humidification process of the nose.
Recognizing Serious or Persistent Issues
While most CPAP-related headaches are resolvable through equipment and setting adjustments, certain symptoms warrant a prompt consultation with a sleep specialist. If a headache is severe, persistent, or accompanied by symptoms such as dizziness or changes in vision, it should be medically evaluated.
Another concern is the possibility of carbon dioxide (CO2) rebreathing, which can occur if the mask’s exhalation ports become blocked or if the equipment is not cleaned properly. Although rare, CO2 rebreathing can lead to a morning headache due to the accumulation of waste gas in the bloodstream.
If a headache does not improve after several weeks of troubleshooting mask fit and humidity settings, a re-evaluation of the core therapy is necessary. A sleep physician can review the machine’s data logs, which provide objective information on residual apnea events, leak rates, and pressure variability. They may suggest a different mask type, a change in pressure prescription, or switching to an auto-adjusting positive airway pressure (APAP) or bilevel positive airway pressure (BiPAP) device to better manage the issue.

